Tag: 200-300

On May 15, 2022, Dou, Shuzhen; Wang, Zhongshun; Chen, Qiye; Lu, Nan published an article.Electric Literature of 144-80-9 The title of the article was One-step fabrication of high-density Si nanotips as SALDI-MS substrate for highly sensitive detection. And the article contained the following:

The high sensitivity of surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) anal. depends on the enhancement of the signal intensity and the reduction of the background. Here, high-d. Si nanotips were prepared as SALDI-MS substrate by taking template-free reactive ion etching for sensitive detection. The high-d. Si nanotips act as tiny antennas to concentrate the laser energy and generate photo-induced electrons on a small area, which promotes desorption and ionization of mol., enhancing the signal intensity. Addnl., the high stability of Si nanotips under laser irradiation ensures low background interference. The applicability of the substrate was demonstrated by the detection of various small mols., e.g., fatty acids, amino acids, environmental pollutants and drugs. In addition, this substrate can be successfully applied for detecting trace small mols. in complex sample, such as 10-9 M verapamil in serum and 10-12 M crystal violet in lake water. Moreover, the banned fungicides left on the fish skin was also detected. The substrate is compatible with imaging, and the endogenous and exogenous substances in fingerprint were visualized by MS imaging. These results demonstrate the easily prepared high-d. Si nanotips SALDI-MS substrate is of high detection sensitivity and great value toward large-scale practical applications. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Electric Literature of 144-80-9

The Article related to silicon nanotip verapamil stearic acid sarcosine saldi ms fabrication, Biochemical Methods: Spectral and Related Methods and other aspects.Electric Literature of 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Xue, Weifeng; Zhang, Haiqin; Wang, Mei; Liu, Ying; Liu, Mengyao; Shen, Baozhen published an article in 2022, the title of the article was Metabolomics-based non-targeted screening analysis of 34 PPCPs in bovine and piscine muscles.Application of 144-80-9 And the article contains the following content:

The metabolomics-based anal. strategy has showed superiority on the non-targeted screening of contaminants, especially for unknown and unexpected (U&U) contaminants in the field of food safety, but data anal. is often the bottleneck of the strategy. In this study, a novel metabolomics-based anal. method via searching for marker compounds was developed on the basis of ultrahigh-performance liquid chromatog.-tandem mass spectrometry (UHPLC-MS/MS) results to accurately, rapidly and comprehensively achieve the non-targeted screening of 34 pharmaceutical and personal care products (PPCPs) as U&U contaminants spiked in bovine and piscine muscle matrixes. Three concentration groups (20, 50 and 100 ng mL-1) were intentionally designed to simulate the control and exptl. groups for the discovery of marker compounds, for which multivariate and univariate analyses were adopted. In multivariate anal., each concentration group was fully separated from the other two groups in PCA and OPLS-DA plots, laying a foundation to distinguish marker compounds among groups. The S-plot, permutation and variable importance in projection (VIP) in OPLS-DA were employed to screen and identify marker compounds, which were further verified by pairwise t-test and fold change judgement in univariate anal. The results indicate that 34 PPCPs spiked in two muscle matrixes were all identified as marker compounds, proving the validity and practicability of this novel metabolomics-based non-targeted screening method, which will exhibit great superiority and broad application prospects, especially in the face of massive PPCPs and various animal matrixes in the field of food safety control. In addition, the limits of detection (LODs) for 34 PPCPs were calculated to be 0.2-2.6μg kg-1 and 0.3-2.1μg kg-1 in bovine and piscine muscle matrixes, resp. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Application of 144-80-9

The Article related to muscle pharmaceutical personal care product metabolomics screening, Biochemical Methods: Spectral and Related Methods and other aspects.Application of 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On February 21, 2020, McKay, Alasdair I.; Altalhi, Weam A. O.; McInnes, Lachlan E.; Czyz, Milena L.; Canty, Allan J.; Donnelly, Paul S.; O’Hair, Richard A. J. published an article.Application of 102-07-8 The title of the article was Identification of the Side Products That Diminish the Yields of the Monoamidated Product in Metal-Catalyzed C-H Amidation of 2-Phenylpyridine with Arylisocyanates. And the article contained the following:

The Ru(II)-catalyzed amidation of 2-arylpyridines with aryl isocyanates via C-H bond activation is less efficient than described previously, due to the formation of a series of side products, which were readily identified using direct infusion electrospray mass spectrometry and high-performance liquid chromatog.-mass spectrometry. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Application of 102-07-8

The Article related to aryl pyridylbenzamide preparation, phenylpyridine arylisocyanate amidation ruthenium catalyst, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Application of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On January 31, 2022, Bardakova, Kseniia N.; Kholkhoev, Bato Ch.; Farion, Ivan A.; Epifanov, Evgenii O.; Korkunova, Olga S.; Efremov, Yuri M.; Minaev, Nikita V.; Solovieva, Anna B.; Timashev, Peter S.; Burdukovskii, Vitaliy F. published an article.Name: 1,3-Diphenylurea The title of the article was 4D Printing of Shape-Memory Semi-Interpenetrating Polymer Networks Based On Aromatic Heterochain Polymers. And the article contained the following:

Most of the presently known thermosensitive shape-memory polymers suitable for 4D printing have insufficient mech. strength and thermal stability that restricts their potential areas of application. Here, new photosensitive compositions (PSCs) based on aromatic heterochain polymers – poly-N,N’-(m-phenylene)isophthalamide (MPA) or poly-2,2′-(p-oxydiphenylene)-5,5′-dibenzimidazole (OPBI) – for DLP printing are proposed. Thermal post-curing and supercritical carbon dioxide (scCO2) are used for post-processing of the structures. During the scCO2 treatment the removal of unreacted monomeric component (N,N-dimethylacrylamide) and its uncrosslinked oligomers is accompanied by the preservation of the initial degree of crosslinking. The more stable shrinkage is observed for the combined post-processing method (T°+scCO2) in the case of OPBI-PSC and after the heat treatment for MPA-PSC specimens. The method of post-processing and the nature of the heterochain polymer strongly affect the mech. properties and thermal resistance of the structures. The tensile strength has the maximum value after the thermal post-treatment (101.1 ± 7.1 and 78.4 ± 5.1 MPa of OPBI-PSC and MPA-PSC, resp.). The intense destruction of the materials is observed at 393 and 408°C for MPA-PSC and OPBI-PSC, resp. Moreover, the 4D-printed structures exhibit excellent shape memory performance at transition temperatures >100°C, thus have a great potential for the use in aerospace, robotics, sensorics. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Name: 1,3-Diphenylurea

The Article related to polybenzimidazole semi interpenetrating polymer network shape memory property, Plastics Fabrication and Uses: Plastic Product Uses and other aspects.Name: 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On July 3, 2014, Spear, Kerry L.; Campbell, Una published a patent.Name: 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione The title of the patent was Preparation of piperidinylindoline derivatives for use as nervous system agents. And the patent contained the following:

Title compounds I [R1 = halo, OH, CN, (un)substituted alkyl, aryl, etc.; R2 = H, halo, OH, alkyl, etc.; or R1 and R2 are taken together with the C atom to which they are attached to form an (un)substituted alkenyl, cycloalkyl or heterocyclyl; R3 = H, OH, halo, CN, alkyl, etc.; R5 = (un)substituted alkyl, cycloalkyl, aryl, heteroaryl, etc.; each X independently = CH or N; Y = absent, O, NH, N-alkyl, or (un)substituted alkylene], and their pharmaceutically acceptable salts, are prepared and disclosed as nervous system agents. Thus, e.g., II was prepared by a multistep procedure (preparation given). Select I were evaluated in CAMP assays on CHO cells expressing the human NOP/MOP receptors (data given). The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Name: 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

The Article related to piperidinylindoline preparation nervous system agent, Heterocyclic Compounds (One Hetero Atom): Pyridines and other aspects.Name: 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On October 13, 2021, Kawamata, Yu; Hayashi, Kyohei; Carlson, Ethan; Shaji, Shobin; Waldmann, Dirk; Simmons, Bryan J.; Edwards, Jacob T.; Zapf, Christoph W.; Saito, Masato; Baran, Phil S. published an article.Synthetic Route of 5455-98-1 The title of the article was Chemoselective Electrosynthesis Using Rapid Alternating Polarity. And the article contained the following:

Challenges in the selective manipulation of functional groups (chemoselectivity) in organic synthesis have historically been overcome either by using reagents/catalysts that tunably interact with a substrate or through modification to shield undesired sites of reactivity (protecting groups). Although electrochem. offers precise redox control to achieve unique chemoselectivity, this approach often becomes challenging in the presence of multiple redox-active functionalities. Historically, electrosynthesis has been performed almost solely by using d.c. (DC). In contrast, applying a.c. (AC) has been known to change reaction outcomes considerably on an anal. scale but has rarely been strategically exploited for use in complex preparative organic synthesis. Here we show how a square waveform employed to deliver elec. current-rapid alternating polarity (rAP)-enables control over reaction outcomes in the chemoselective reduction of carbonyl compounds, one of the most widely used reaction manifolds. The reactivity observed cannot be recapitulated using DC electrolysis or chem. reagents. The synthetic value brought by this new method for controlling chemoselectivity is vividly demonstrated in the context of classical reactivity problems such as chiral auxiliary removal and cutting-edge medicinal chem. topics such as the synthesis of PROTACs. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Synthetic Route of 5455-98-1

The Article related to electrochem chemoselective reduction ketone rapid alternating polarity, Heterocyclic Compounds (One Hetero Atom): General and other aspects.Synthetic Route of 5455-98-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On May 15, 2022, Dou, Shuzhen; Wang, Zhongshun; Chen, Qiye; Lu, Nan published an article.Electric Literature of 144-80-9 The title of the article was One-step fabrication of high-density Si nanotips as SALDI-MS substrate for highly sensitive detection. And the article contained the following:

The high sensitivity of surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) anal. depends on the enhancement of the signal intensity and the reduction of the background. Here, high-d. Si nanotips were prepared as SALDI-MS substrate by taking template-free reactive ion etching for sensitive detection. The high-d. Si nanotips act as tiny antennas to concentrate the laser energy and generate photo-induced electrons on a small area, which promotes desorption and ionization of mol., enhancing the signal intensity. Addnl., the high stability of Si nanotips under laser irradiation ensures low background interference. The applicability of the substrate was demonstrated by the detection of various small mols., e.g., fatty acids, amino acids, environmental pollutants and drugs. In addition, this substrate can be successfully applied for detecting trace small mols. in complex sample, such as 10-9 M verapamil in serum and 10-12 M crystal violet in lake water. Moreover, the banned fungicides left on the fish skin was also detected. The substrate is compatible with imaging, and the endogenous and exogenous substances in fingerprint were visualized by MS imaging. These results demonstrate the easily prepared high-d. Si nanotips SALDI-MS substrate is of high detection sensitivity and great value toward large-scale practical applications. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Electric Literature of 144-80-9

The Article related to silicon nanotip verapamil stearic acid sarcosine saldi ms fabrication, Biochemical Methods: Spectral and Related Methods and other aspects.Electric Literature of 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Xue, Weifeng; Zhang, Haiqin; Wang, Mei; Liu, Ying; Liu, Mengyao; Shen, Baozhen published an article in 2022, the title of the article was Metabolomics-based non-targeted screening analysis of 34 PPCPs in bovine and piscine muscles.Application of 144-80-9 And the article contains the following content:

The metabolomics-based anal. strategy has showed superiority on the non-targeted screening of contaminants, especially for unknown and unexpected (U&U) contaminants in the field of food safety, but data anal. is often the bottleneck of the strategy. In this study, a novel metabolomics-based anal. method via searching for marker compounds was developed on the basis of ultrahigh-performance liquid chromatog.-tandem mass spectrometry (UHPLC-MS/MS) results to accurately, rapidly and comprehensively achieve the non-targeted screening of 34 pharmaceutical and personal care products (PPCPs) as U&U contaminants spiked in bovine and piscine muscle matrixes. Three concentration groups (20, 50 and 100 ng mL-1) were intentionally designed to simulate the control and exptl. groups for the discovery of marker compounds, for which multivariate and univariate analyses were adopted. In multivariate anal., each concentration group was fully separated from the other two groups in PCA and OPLS-DA plots, laying a foundation to distinguish marker compounds among groups. The S-plot, permutation and variable importance in projection (VIP) in OPLS-DA were employed to screen and identify marker compounds, which were further verified by pairwise t-test and fold change judgement in univariate anal. The results indicate that 34 PPCPs spiked in two muscle matrixes were all identified as marker compounds, proving the validity and practicability of this novel metabolomics-based non-targeted screening method, which will exhibit great superiority and broad application prospects, especially in the face of massive PPCPs and various animal matrixes in the field of food safety control. In addition, the limits of detection (LODs) for 34 PPCPs were calculated to be 0.2-2.6μg kg-1 and 0.3-2.1μg kg-1 in bovine and piscine muscle matrixes, resp. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Application of 144-80-9

The Article related to muscle pharmaceutical personal care product metabolomics screening, Biochemical Methods: Spectral and Related Methods and other aspects.Application of 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On July 3, 2014, Sugawara, Yasuhisa; Sakata, Koji; Tomioka, Yasuhiro; Demizu, Hiroyuki; Satoh, Hiroki published a patent.Formula: C11H9NO3 The title of the patent was Solid electrolytic capacitor. And the patent contained the following:

Provided is a solid electrolytic capacitor having a low initial equivalent series resistance (ESR) in which the ESR increase with time can be suppressed. It is a solid electrolytic capacitor, including an electroconductive polymer layer, a graphite layer on the electroconductive polymer layer, and a silver layer on the graphite layer, wherein the electroconductive polymer layer and the graphite layer, and/or, the graphite layer and the silver layer are bonded by a chem. bond. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Formula: C11H9NO3

The Article related to capacitor electrolytic solid low equivalent series resistance, Electric Phenomena: Capacitors, Dielectrics, Insulators, Electrets and other aspects.Formula: C11H9NO3

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Ali, Mohammad; Zarchi, Karimi; Tarabsaz, Ali published an article in 2015, the title of the article was Ring Opening of Epoxides by Using Cross-Linked Poly(4-Vinylpyridine)-Supported Thiocyanate in the Presence of Polymer-Supported Sulfuric Acid Under Solvent-Free Conditions.Application In Synthesis of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione And the article contains the following content:

Cross-linked poly(4-vinylpyridine)-supported thiocyanate ion, [P4-VP]SCN, is introduced as recyclable polymeric reagent for the efficient and regioselective conversion of epoxides to thiocyanohydrins in the presence of cross-linked poly(4-vinylpyridine)-supported sulfuric acid, [P4-VP]H2SO4, as a solid proton source and as catalyst under solvent-free conditions. The ring-opening reaction of epoxides take place very fast under solvent-free conditions and the regioselective thiocyanohydrins are prepared in high yields at 65°C. The present method offers advantages such as short reaction time, simple reaction work-up, and the polymeric reagents can be regenerated and reused several times without significant loss of their activity. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Application In Synthesis of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

The Article related to epoxide ring opening polymer supported reagent solvent free, Plastics Manufacture and Processing: Chemical Properties Of Resins and other aspects.Application In Synthesis of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics