Tag: 200-300

On October 12, 2022, Zhong, Pinyong; Wu, Junran; Liu, Jin-Biao; Luo, Nianhua published an article.Recommanded Product: 1,3-Diphenylurea The title of the article was Atmosphere-controlled selective synthesis of ureas and thioureas from isothiocyanates. And the article contained the following:

An atmosphere-controlled selective synthesis of ureas and thioureas from isothiocyanates in the presence of 4-dimethylaminopyridine is described. A series of disubstituted ureas and thioureas were prepared in air and nitrogen atm., resp. This protocol employs benign reagents and exhibits good chemoselectivity and practicality. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Recommanded Product: 1,3-Diphenylurea

The Article related to urea thiourea preparation chemoselective atm controlled, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ureas, Carbamic Acids, Guanidines, and Their Sulfur-Containing Analogs and other aspects.Recommanded Product: 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On January 7, 2021, Angel, Matthew; Kostas, Franklin; Rohde, Christopher published a patent.Related Products of 5455-98-1 The title of the patent was Preparation of cationic lipids for delivery of nucleic acids to cells. And the patent contained the following:

Cationic lipids of formula I [n = 1-15] are prepared for use in liposomes for the delivery of nucleic acids to cells. Thus, I (n = 4) was prepared, and used for mRNA delivery to a human subject by intradermal injection. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Related Products of 5455-98-1

The Article related to lipid cationic preparation liposome nucleic acid delivery, Biomolecules and Their Synthetic Analogs: Prostaglandins and Other Arachidonic Acid Cascade Substances, Thromboxanes, Fatty Acids and other aspects.Related Products of 5455-98-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On December 10, 2019, Angel, Matthew; Kostas, Franklin; Rohde, Christopher published a patent.COA of Formula: C11H9NO3 The title of the patent was Cationic lipids and transfection methods. And the patent contained the following:

Cationic lipids of formula I [n = 1-15] are prepared which are used in liposomes for delivering nucleic acids to cells. Thus, I (n = 4) (DHDLinS) was prepared, and transfected human epidermal keratinocytes with RNA. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).COA of Formula: C11H9NO3

The Article related to cationic lipid preparation liposome nucleic acid delivery, Biomolecules and Their Synthetic Analogs: Prostaglandins and Other Arachidonic Acid Cascade Substances, Thromboxanes, Fatty Acids and other aspects.COA of Formula: C11H9NO3

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On October 3, 2019, Bi, Yingzhi; Dorsey, Bruce D.; Fan, Yi; Moore, Christopher Brooks; Nguyen, Duyan published a patent.Product Details of 5455-98-1 The title of the patent was Preparation of substituted 1,1′-biphenyl compounds and analogues thereof, and methods for using them for treatment of HBV and HDV infections. And the patent contained the following:

The invention is related to the preparation of compounds I [X1 = CH, N; X2 = R2a = OCH2**, CH2O**, CONH**, NHCO**, wherein the bond marked with ** is to the Ph ring carbon marked with *; R1a, R1b = independently H, alkyl, alkoxy, CN, halo, haloalkyl; R1c = H, alkyl, OH, alkoxy optionally substituted; R2a = alkyl, alkoxy, (CH2)1-3(optionally substituted phenyl), etc.; R3a = CHO, COOH and derivatives, CONH2 and derivatives, etc.; R4a = halo, CN, alkyl], including substituted 3,3′-bis(phenoxymethyl)-1,1′-biphenyl compounds and their analogs, their salts, solvates, geometric isomers, stereoisomers, tautomers or any mixtures thereof, and compositions comprising them, that can be used to treat or prevent hepatitis B virus (HBV) and/or hepatitis D virus (HDV) infections in a patient. Thus, II was prepared from (2-methyl-3-phenylphenyl)methanol using 2,4-dihydroxybenzaldehyde, 3-(bromomethyl)benzonitrile and ethane-1,2-diamine. II displayed an IC50 of 0.28 in a PD-L1 HTRF assay. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Product Details of 5455-98-1

The Article related to biphenyl analog preparation pd1 pdl1 inhibitor antiviral hbv hdv, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amides, Amidines, Imidic Esters, Hydrazides, and Hydrazonic Esters and other aspects.Product Details of 5455-98-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On September 30, 2009, Shyamala, M.; Arulanantham, A. published an article.Category: amides-buliding-blocks The title of the article was Aegle marmelos as effective corrosion pickling inhibitor on mild steel in hydrochloric acid. And the article contained the following:

In this study, the corrosion inhibition effect of aqueous extract of Aegle marmelos in 1N hydrochloric acid has been investigated by weight loss, gasometric, potentiodynamic polarization and impedance methods. The Aegle marmelos was found to be effective corrosion pickling inhibitor. The effect of immersion time revealed that the extracts of Aegle marmelos has maximum inhibition efficiency of 97.5 % in presence of an optimum concentration of 8 % volume/volume of the extract at 3 h of immersion time. Similarly, in gasometric method, maximum efficiency was found to be 97.1 % in the same optimum concentration It was confirmed by potentiodynamic polarization and impedance methods, which showed a maximum efficiency of 97.5 % and 96.6 % resp. in the concentration 8 % in volume/volume Potentiodynamic polarization studies indicated that the plant extract behaves as mixed type inhibitor. The adsorption of Aegle marmelos follows Langmuir adsorption isotherm. The inhibition action is due to presence of the alkaloid aegeline in the leaves of Aegle marmelos. The protective film formed on the surface of the mild steel was confirmed by SEM studies. The experimental process involved the reaction of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas: 456-12-2).Category: amides-buliding-blocks

The Article related to hydrochloric acid mild steel corrosion pickling inhibitor aegle marmelos, Ferrous Metals and Alloys: Corrosion (If The Primary Interest Is In The Metal), Erosion, Cavitation, Tribology, and Oxidation and other aspects.Category: amides-buliding-blocks

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On September 2, 2002, Bhattacharya, Gautam; Salem, Manar M.; Werbovetz, Karl A. published an article.Formula: C6H5ClN2O4S The title of the article was Antileishmanial dinitroaniline sulfonamides with activity against parasite tubulin. And the article contained the following:

Novel dinitroaniline sulfonamides based on the herbicide oryzalin were synthesized and evaluated for activity against the parasitic protozoan Leishmania donovani and against leishmanial tubulin, the putative antiparasitic target of oryzalin. A subset of these compounds possess more activity against both Leishmania and the target protein in vitro. Compound I displays improved potency against leishmanial tubulin and is 13.4-fold more active against L. donovani axenic amastigotes than oryzalin. The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Formula: C6H5ClN2O4S

The Article related to dinitroaniline sulfonamide preparation, antiparasitic leishmanial tubulin polymerization inhibiting aniline dinitro sulfonamide derivative, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Formula: C6H5ClN2O4S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On February 28, 1982, Plakidin, V. L.; Vostrova, V. N. published an article.Synthetic Route of 97-09-6 The title of the article was Reaction of 2,4-disubstituted chlorobenzenes with 3-alkylamino and 3-dialkylaminopropionitriles. And the article contained the following:

Reaction of I (R, R1 = H, NO2; NO2, NO2; NO2, Cl; NO2, SO2Me; NO2, SO2NH2; NO2, SO2NMe2; CN, NO2) with R22NCH2CH2CN (R2 = Me, Et) at 65-170° gave (via the quaternary salt) II (13 compounds), and with R2NHCH2CH2CN (R2 = Me, Et) at 20-130° gave III (11 compounds). At ∼130° cleavage of the cyanomethyl group from III was observed The experimental process involved the reaction of 3-Nitro-4-chlorobenzenesulfonamide(cas: 97-09-6).Synthetic Route of 97-09-6

The Article related to substituted chlorobenzene amino nitrile, aniline derivative, benzenamine derivative, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Amines, Amine Oxides, Imines, and Quaternary Ammonium Compounds and other aspects.Synthetic Route of 97-09-6

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Yang, Jinchen; Chen, Ling; Dong, Yibo; Zhang, Jinli; Wu, Yangjie published an article in 2022, the title of the article was Di-tert-butyl peroxide (DTBP)-mediated synthesis of symmetrical N,N’-disubstituted urea/thiourea motifs from isothiocyanates in water.Application In Synthesis of 1,3-Diphenylurea And the article contains the following content:

A direct approach to N,N’-disubstituted urea/thiourea from the self-condensation reactions of isothiocyanates in water has been developed. This access tolerated a wide range of functional groups on the aromatic ring, providing a practical and environment-friendly process to N,N’-disubstituted urea/thiourea in moderate to excellent yields from safe and easily available starting materials. A plausible mechanism of the desulfurization self-condensation reaction for urea was also proposed and the role of di-tert-Bu peroxide (DTBP) and copper catalyst in the present strategy was demonstrated with the help of ESI mass spectrometry of intermediate studies. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Application In Synthesis of 1,3-Diphenylurea

The Article related to urea thiourea preparation green chem, isothiocyanate desulfurization self condensation ditert butyl peroxide, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Ureas, Carbamic Acids, Guanidines, and Their Sulfur-Containing Analogs and other aspects.Application In Synthesis of 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On September 8, 2020, Yang, Wenbo; Sukhanov, Andrei A.; Lim, Jong Hyeon; Li, Xiaoxin; Meng, Yinshan; Zhao, Jianzhang; Sun, Haoling; Lee, Jin Yong; Gurzadyan, Gagik G.; Voronkova, Violeta K. published an article.Recommanded Product: 102-07-8 The title of the article was N^N Pt(II) Bisacetylide Complexes with Oxoverdazyl Radical Ligands: Preparation, Photophysical Properties, and Magnetic Exchange Interaction between the Two Radical Ligands. And the article contained the following:

To study the effect of a stable radical on the photophys. properties of a phosphorescent Pt(II) coordination framework and the intramol. magnetic interaction between radical ligands in the N^N Pt(II) bisacetylide complexes, authors prepared a series of N^N Pt(II) bis(acetylide) complexes with oxoverdazyl radical acetylide ligands. The linker between the Pt(II) center and the spin carrier was systematically varied, to probe the effect on the sign and magnitude of the spin exchange interactions between the radical ligands and photophys. properties. The complexes were studied with steady-state and femtosecond/ns transient absorption spectroscopy, continuous-wave ESR spectroscopy, and d. functional theory (DFT) computations. The transient absorption spectral studies show that the doublet excited state of the radicals are short-lived (τD ≈ 2 ps) and nonfluorescent. Moreover, the intrinsic long-lived triplet excited state (τT = 1.2μs) of the Pt(II) coordination center was efficiently quenched by the radical (τT = 6.9 ps for one representative radical Pt(II) complex). The intramol. magnetic interaction between the radical ligands through the diamagnetic Pt(II) atom was studied with temperature-dependent EPR spectroscopy; antiferromagnetic exchange interaction (-J S1S2, J = -5.4 ± 0.1 cm-1) for the complex with the shortest radical-radical distance through bridge fragments was observed DFT computations give similar results for the sign and magnitude of the J values. For complexes with larger inter-radical distance, however, very weak coupling between the radical ligands was observed (|J| < 0.7 cm-1). The results are useful for the study of the effect of a radical on the photophys. properties of the phosphorescent transition-metal complexes. A series of Pt(II) complexes containing oxoverdazyl radical ligands was prepared The length of the linker between Pt(II) center and spin carrier exerts significant effect on photophys. and magnetic property. The intrinsic long-lived triplet excited state of the Pt(II) coordination center was efficiently quenched by the presence of the radical. Antiferromagnetic interaction between the two radical ligands was observed The sign and the magnitude of the electronic spin-spin exchange was reproduced with DFT computations. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Recommanded Product: 102-07-8

The Article related to oxoverdazyl radical platinum bisacetylide preparation mol structure calculation electrochem, photophys magnetic exchange oxoverdazyl radical platinum bisacetylide complex and other aspects.Recommanded Product: 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On February 15, 2022, Misaela, Francisco-Marquez; Alexander, Perez de la Luz; Catalina, Soriano-Correa; Carolina, Barrientos-Salcedo; Ignacio, Sainz-Diaz C. published an article.Formula: C8H10N2O3S The title of the article was Tautomerism and IR spectroscopy of arylsulfonamides by quantum mechanical calculations. And the article contained the following:

The mol. structures of sulfonamides are interesting for evaluating their mobility in soils and preparing composite complexes for optimizing the use of these drugs. In this work, the mol. structures of several arylsulfonamides along with conformational anal. and tautomerism were investigated theor. The spectroscopical properties of several arylsulfonamides, were also studied at mol. level by using a computational modeling at quantum mechanics level. Besides, the controversial exptl. results found in the IR (IR) spectroscopy bands assignments of solid sulfonamides pushed us up to study computationally the crystal structure of sulfamethazine for clarifying previous assignment discrepancies. The previously proposed polymorphism in the crystal structure of this drug has been also clarified in this work. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Formula: C8H10N2O3S

The Article related to aryl sulfonamide tautomerism crystal polymorphism ir spectra, Physical Organic Chemistry: Absorption, Emission, Reflection, and Scattering Spectra (Ultraviolet and Visible, Infrared and Fourier Transform Infrared, Raman, Microwave, Photoelectron, Fluorescence, Phosphorescence, etc.) and other aspects.Formula: C8H10N2O3S

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics