Tag: 200-300

On November 8, 2021, Karimi, Farzaneh; Shariatipour, Monire; Heydari, Akbar published an article.Safety of 1,3-Diphenylurea The title of the article was Deep Eutectic Solvent Mediated Carbonylation of Amines and Alcohols by Using Dimethyl Carbonate: Selective Symmetrical Urea and Organic Carbonate Synthesis. And the article contained the following:

This work presented one-pot synthesis of sym. organic carbonates and ureas by employing cheap and biodegradable deep eutectic solvent as the catalyst and reaction media. The effect of different reaction parameters such as temperature, DMC/amines and alcs. ratio and reaction time were investigated on the reaction efficiency. This new protocol provided a simple, fast, and sustainable approach and proceeded with high efficiency with aliphatic and aromatic amines and alcs. as well. Finally, applicability of this methodol. was also examined for reaction of nucleophiles such as Ph hydrazine and Ph glycine with di-Me carbonate. Interestingly, it was found that this reaction system obtained good yields of product for both of them. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Safety of 1,3-Diphenylurea

The Article related to sym urea preparation, amine dimethyl carbonate carbonylation deep eutectic solvent mediated, carbonate preparation, alc dimethyl carbonate carbonylation deep eutectic solvent mediated and other aspects.Safety of 1,3-Diphenylurea

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 1, 2021, Guo, Ruonan; Li, Yunhe; Chen, Ying; Liu, Yu; Niu, Bihui; Gou, Jianfeng; Cheng, Xiuwen published an article.Recommanded Product: 144-80-9 The title of the article was Efficient degradation of sulfamethoxazole by CoCu LDH composite membrane activating peroxymonosulfate with decreased metal ion leaching. And the article contained the following:

In this study, we prepared two types of composite membranes decorated with CoCu layered double hydroxide (LDH) nanoparticles, i.e. LDH@Calotropis gigantean fiber (LDH@CGF) and LDH@polyvinylidene fluoride (LDH@PVDF) for the first time. Besides, the application potential of different types of composite functional membranes based on LDH in PMS activation system was compared. Both of the LDH-based composite membranes exhibited excellent activity in peroxymonosulfate (PMS) activation process. More importantly, the composite membrane could be separated from the treated water to meet the need of practical application. The superior composite membrane was identified as LDH@PVDF, which was with excellent PMS activation capability and pretty lower metal ions leaching concentration (cobalt 0.044 mg L-1, copper 0.026 mg L-1). And then, LDH@PVDF was employed to investigate the PMS activation performance in various pharmaceutical pollutants removal processes. Besides, the activity of LDH@PVDF for SMX degradation in real aquatic environment (tap water and wastewater) was detected, proving the wide practical applicability of LDH@PVDF membrane. Finally, the possible SMX degradation pathway and PMS activation mechanism occurring in LDH-based composite membrane/PMS system were proposed. Hence, this study for LDH-based membranes construction may provide new insights into the environmentally-friendly catalytic membranes preparation and practical application in wastewater treatment. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Recommanded Product: 144-80-9

The Article related to sulfamethoxazole degradation cobalt copper layered double hydroxide composite membrane, composite membrane peroxymonosulfate metal ion leaching pharmaceutical wastewater treatment and other aspects.Recommanded Product: 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On December 29, 2021, Xiao, Shouchun; Lv, Shengchen; Cheng, Zheng; Hu, Caiwei; Li, Pengxi; Nan, Fang; Liu, Xueke; Liu, Donghui; Zhou, Zhiqiang; Wang, Peng published an article.COA of Formula: C13H12N2O The title of the article was A Simple Method for the Determination of Pharmaceutical and Personal Care Products in Fish Tissue Based on Matrix Solid-Phase Dispersion. And the article contained the following:

A simple and effective pretreatment method based on matrix solid-phase dispersion was developed for the determination of pharmaceutical and personal care products (PPCPs) and their metabolites in fish by high-performance liquid chromatog. tandem mass spectrometry. The type and amount of dispersant, adsorbent, and eluting solvent were optimized by a single-factor experiment and Box-Behnken design. Under the optimal conditions with 2.5 g of Florisil as a dispersant, 500 mg of C18 as an adsorbent, and 5 mL of acetonitrile as an eluting solvent, the recoveries ranged from 70.4 to 99.9% with relative standard deviations less than 10.5%, and the limits of quantitation ranged from 0.13 to 1.01μg/kg. The developed method was successfully applied to detect PPCPs in marketed fish, and five PPCPs, including triclocarban, sulfadiazine, sulfadimidine, sulfamethoxazole, and carbamazepine, were detected at trace levels. The proposed method, which has the advantages of short anal. time, less solvent consumption, and high sensitivity, can be used for the determination of trace PPCPs in fish. The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).COA of Formula: C13H12N2O

The Article related to fish contamination pharmaceutical personal care product matrix solid dispersion, box−behnken design, fish, matrix solid-phase dispersion, pharmaceutical and personal care products and other aspects.COA of Formula: C13H12N2O

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Wan, Yameng; Wu, Hao; Ma, Nana; Zhao, Jie; Zhang, Zhiguo; Gao, Wenjing; Zhang, Guisheng published an article in 2021, the title of the article was De novo design and synthesis of dipyridopurinone derivatives as visible-light photocatalysts in productive guanylation reactions.Related Products of 102-07-8 And the article contains the following content:

De novo design and synthesis of a series of 6H-dipyrido[1,2-e:2′,1′-i]purin-6-ones (DPs), e.g., I as a new class of visible-light photoredox catalysts (PCs) was described. The synthesized DPs showed their λAbs(max) values in 433-477 nm, excited state redox potentials E*1/2 red and E*1/2 ox in 1.15-0.69 eV and -1.41 to -1.77 eV (vs. SCE), resp. As a representative, DP I enabled productive guanylation of amines, including 1°, 2°, and 3°-alkyl primary amines, secondary amines, aryl and heteroaryl amines, amino-nitrile, amino acids and peptides as well as propynylamines and α-amino esters giving diversities in biol. important guanidines and cyclic guanidines. The photocatalytic efficacy of DP I in guanylation overmatched commonly used Ir and Ru polypyridyl complexes, and some organic PCs. Other salient merits of this method included broad substrate scope and functional group tolerance, gram-scale synthesis, and versatile late-stage derivatizations that led to a derivative 81 exhibiting 60-fold better anticancer activity against Ramos cells with IC50 of 0.086μM than that of clin. drug ibrutinib (5.1μM). The experimental process involved the reaction of 1,3-Diphenylurea(cas: 102-07-8).Related Products of 102-07-8

The Article related to dipyridopurinone photocatalyst preparation dft, guanidine photochem preparation antiproliferative, amine thiourea guanylation dipyridopurinone photocatalyst visible light induced and other aspects.Related Products of 102-07-8

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 31, 2021, Liu, Yanhua; Chen, Yu; Feng, Mengjuan; Chen, Jianqiu; Shen, Weitao; Zhang, Shenghu published an article.Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Occurrence of antibiotics and antibiotic resistance genes and their correlations in river-type drinking water source, China. And the article contained the following:

The occurrence and distribution of antibiotics and antibiotic resistance genes (ARGs) in natural water has attracted worldwide attention. Antibiotic and ARG pollution in the surface water of drinking water sources might directly/indirectly affect human health. In this study, the distribution of 38 antibiotics, 10 ARGs, 2 integrons, and 16S r DNA in river-type water sources in a large city of China were monitored in winter, which was a period with high level of antibiotic pollution. The results showed that 20 antibiotics were detected with different detection frequencies. The antibiotic pollution in Dec. 2019 was relatively high, with the total concentrations of antibiotics ranging from 281.95 to 472.42 ng/L, followed by that in Jan. 2020 (191.70-337.29 ng/L) and Nov. 2019 (161.25-309.72 ng/L). Sulfacetamide was dominant in Nov. 2019 (23.52-219.00 ng/L) and in Jan. 2020 (113.18-209 ng/L), while norfloxacin in Dec. 2019 (146.72-290.20 ng/L). All the target antibiotics posed low or medium risk for aquatic organisms, and posed low health risk for mankind. Sul1 and erm36 were the predominant ARGs, and intI1 was the predominant integron in drinking water sources. Only tetA showed pos. correlations with its corresponding antibiotic (tetracycline). The rest of ARGs showed no correlations with antibiotics or pos. / neg. correlations with their non-corresponding antibiotics. Overall, the antibiotics and ARG pollution in these water sources was relatively low. These findings provided some reference data for the distribution of antibiotics and ARGs in river-type drinking water sources of large cities in China. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to antibiotics antibiotic resistance gene drinking water pollution china, antibiotic residues, antibiotic resistance genes, risk assessment, river-type drinking water, yangtze river and other aspects.Quality Control of N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Mohammed, Magdy M. D.; Ibrahim, Nabaweya A.; El-Sakhawy, Fatma S.; Mohamed, Khaled M.; Deabes, Doaa A.-H. published an article in 2016, the title of the article was Two new cytotoxic furoquinoline alkaloids isolated from Aegle marmelos (Linn.) Correa.Application In Synthesis of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide And the article contains the following content:

Two new cytotoxic furoquinoline alkaloids were isolated from the leaves of Aegle marmelos (Linn.) Correa; one from the total alkaloidal fraction (acid/base shake-out method) of the CHCl3 extract and identified as 7,8-dihydroxy-4-hydrofuroquinoline and named trivially as Aegelbine-A. The other new alkaloid isolated from the pet. ether extract and identified as 4-hydro-7-hydroxy-8-prenyloxyfuroquinoline and named trivially as Aegelbine-B, together with a known alkaloid; aegeline and a known phenolic acid; ρ-hydroxybenzoic acid. The structures of all the isolated compounds were established based on 1D and 2D NMR spectroscopy and HR-ESI/MS. The cytotoxic activity of the isolated compounds was evaluated in vitro against HepG-2, PC3, A549 and MCF-7 cell lines. The obtained results revealed promising activity with structure-based relationship which is discussed briefly. The experimental process involved the reaction of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide(cas: 456-12-2).Application In Synthesis of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide

The Article related to mol structure cytotoxic furoquinoline alkaloid aegle aegelbine human antitumor, aegle marmelos (linn.) correa, cytotoxicity, furoquinoline alkaloids, rutaceae, structure–activity relationship studies and other aspects.Application In Synthesis of N-(2-Hydroxy-2-(4-methoxyphenyl)ethyl)cinnamamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On November 30, 2022, Wang, Pu; Lou, Xiaoyi; Chen, Qianqian; Liu, Yujing; Sun, Xiaohu; Guo, Yaoguang; Zhang, Xiaojiao; Wang, Ruixue; Wang, Zhaohui; Chen, Shuai; Zhang, Li; Zhang, Rui-Qin; Guan, Jie published an article.Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide The title of the article was Spent LiFePO4: An old but vigorous peroxymonosulfate activator for degradation of organic pollutants in water. And the article contained the following:

Iron-based catalysts have been demonstrated to activate peroxymonosulfate (PMS) to generate reactive radicals, which is however limited by their complex preparation process, high costs and inefficiency for practical applications. Herein we obtain spent LiFePO4 (SLFP), with powerful catalytic capacity by a simple one-step treatment of the retired LiFePO4 cathode material, for PMS activation to decontaminate organic pollutants. Lithium defects and oxygen vacancies in SLFP play critical roles for PMS utilization, further confirmed by d. functional theory (DFT) calculations SLFP materials rapidly adsorb PMS, and the surface PMS is activated by Fe(II) to generate radicals, with ·OH playing a major role for the degradation of organics after multi-step reactions. The SLFP/PMS process is finally validated for ability to remove organic contaminants and potential environmental application. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide

The Article related to iron lithium phosphate catalyst peroxymonosulfate activator organic pollutant degradation, advanced oxidation processes, catalysis, hydroxyl radical, peroxymonosulfate, quantum chemical calculations and other aspects.Application In Synthesis of N-((4-Aminophenyl)sulfonyl)acetamide

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On August 31, 2021, Zhao, Wentao; Jiang, Rui; Guo, Wenping; Guo, Chao; Li, Shilei; Wang, Juanqiang; Wang, Shouwei; Li, Yingying published an article.Product Details of 144-80-9 The title of the article was Screening and Analysis of Multiclass Veterinary Drug Residues in Animal Source Foods using UPLC-Q-Exactive Orbitrap/MS. And the article contained the following:

A rapid, simple, and sensitive method of detecting veterinary drug residues in animal food sources, including poultry and pork, was developed and validated. The method was optimized for over 155 veterinary drugs of 21 different classes. Sample pretreatment included a simple solid-liquid extraction step with 0.2% formic acid-acetonitrile-water and a purification step with a PRiME HLB (hydrophile-lipophile balance) solid-phase extraction cartridge. Data were collected using ultra-high-performance liquid chromatog. coupled to Quadrupole-Exactive Orbitrap mass spectrometry. The limits of detection of 155 veterinary drugs ranged from 0.1μg/kg to 10μg/kg. The recovery rates were between 79.2 and 118.5% in all matrixes studied, with relative standard deviation values less than 15% (n = 6). The evaluated method allows the reliable screening, quantification, and identification of 155 veterinary drug residues in animal source food and has been successfully applied in authentic samples. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Product Details of 144-80-9

The Article related to veterinary drug residue animal source food uplcqexactive orbitrap ms, animal source foods, qualitative screening, quantitative determination, uplc-q-exactive orbitrap/ms, veterinary drug residues and other aspects.Product Details of 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

On September 20, 2021, Zhang, Lili; Zhang, Cheng; Lian, Keting; Ke, Dongfang; Xie, Ting; Liu, Chongxuan published an article.Synthetic Route of 144-80-9 The title of the article was River restoration changes distributions of antibiotics, antibiotic resistance genes, and microbial community. And the article contained the following:

Although river restoration has been increasingly implemented to restore water quality in ecosystems, its effect on the removal of emerging pollutant antibiotics, and their resultant influence on microbial community structure and functions in river water is still unclear. This study investigated the changes of antibiotics, antibiotic resistant genes (ARGs), microbial communities, and their spatial distributions in a megacity river before and after river restoration. Results indicated that although the restoration activities including riverbed dredging, riverbank hardening, sewage and storm water separation and re-pipelining improved water quality such as by decreasing total phosphorus (TP) content from 4.60 mg/L in 2018 to 0.98 mg/L in 2020, the antibiotic concentrations in river water increased. Total antibiotic concentrations in the water samples were higher in 2020 (506.89-6952.50 ng/L) than those in 2018 (137.93-1751.51 ng/L), likely caused by increased usage of antibiotics in 2020 for COVID-19 treatment. The spatial distributions of antibiotics were less varied likely as a result of less retardation and fast mixing during antibiotic transport. The result also found that the abundance of Actinobacteria and Proteobacteria, and their correlations with ARGs increased. The spatial distributions of ARGs and microbial communities became less varied in the river water, consistent with the antibiotic variations before and after river restoration. Physicochem. changes such as decreased TP and dissolved organic carbon content may also be a factor. The results indicated that the current river restoration efforts were not effective in removing antibiotics, and implied that further studies are needed to investigate their subsequent transformation and transport, and to assess their risks to the health of ecosystems. The experimental process involved the reaction of N-((4-Aminophenyl)sulfonyl)acetamide(cas: 144-80-9).Synthetic Route of 144-80-9

The Article related to antibiotic resistance gene microorganism maozhou river restoration, antibiotic resistance genes, antibiotics, maozhou river, river contamination, river restoration, riverine microbial community and other aspects.Synthetic Route of 144-80-9

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Li, Li; Schug, Kevin A. published an article in 2014, the title of the article was Continuous-flow extractive desorption electrospray ionization coupled to normal phase separations and for direct lipid analysis from cell extracts.Computed Properties of 5455-98-1 And the article contains the following content:

Normal phase liquid chromatog. is a common mode for chiral separations Many chiral amines are used as drugs or are important intermediates for drug synthesis. Electrospray ionization mass spectrometry is well known for its high sensitivity. However, when using normal phase liquid chromatog., electrospray ionization is hampered by the poor ionization efficiency of analytes from organic eluents. Continuous-flow extractive desorption electrospray ionization, which introduces the eluents through a hypodermic needle into the electrospray plume is demonstrated here for its success to interface normal phase liquid chromatog. to mass spectrometry detection. Such an approach was shown to be as or more sensitive than UV detection for a selected set of aromatic amine-functionalized enantiomers. Also demonstrated is the direct infusion of cell extracts to monitor phospholipids from three different bacterial cells. Despite their presence in non-electrospray-ionization-friendly extraction solvents, continuous-flow extractive desorption electrospray ionization enabled the sensitive detection of phospholipids and the ability to tune ion forms through incorporation of different spray modifiers. The experimental process involved the reaction of 2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione(cas: 5455-98-1).Computed Properties of 5455-98-1

The Article related to extractive desorption electrospray mass spectrometry lipid cell, liquid chromatog bacteria phospholipid, ambient ionization, chiral separation, direct analysis, mass spectrometry, phospholipids and other aspects.Computed Properties of 5455-98-1

Referemce:
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics