Final Thoughts on Chemistry for 90-16-4

Category: amides-buliding-blocks. About Benzo[d][1,2,3]triazin-4(3H)-one, If you have any questions, you can contact Zhang, RF; Guo, W; Wang, GL; Chen, XL; Li, Z; Xu, XY or concate me.

Category: amides-buliding-blocks. In 2020 BIOORG MED CHEM LETT published article about SYSTEMIC ACQUIRED-RESISTANCE; ROTYLENCHULUS-RENIFORMIS; ELICITORS; NEMATICIDES; EFFICACY; TOMATO; PLANTS; SPP. in [Zhang, Ruifeng; Wang, Gaolei; Chen, Xiulei; Li, Zhong; Xu, Xiaoyong] East China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China; [Guo, Wei] China Crop Protect Ind Assoc, Beijing 100723, Peoples R China in 2020, Cited 28. The Name is Benzo[d][1,2,3]triazin-4(3H)-one. Through research, I have a further understanding and discovery of 90-16-4.

Based on the characteristic of benzo[d][1,2,3]thiadiazole to induce the systemic acquired resistance and improve the immunity of plants, benzo[d][1,2,3]thiadiazole was introduced into 1,2,3-benzotriazin-4-one, thirty-one novel 1,2,3-benzotriazin-4-one derivatives containing benzo[d][1,2,3]thiadiazole were designed and synthesized. Nematicidal activity showed that most of the synthesized compounds exhibited great inhibitory activity in vivo against Meloidogyne incognita at 20 mg/L. Among 31 tested compounds, A2 and A3 showed an excellent nematicidal activity with the inhibition rate of 50.4% and 53.1% at the concentration of 1.0 mg/L, respectively. The influence of substituent type and position was investigated. The relationship between structure and activity was also preliminary analyzed.

Category: amides-buliding-blocks. About Benzo[d][1,2,3]triazin-4(3H)-one, If you have any questions, you can contact Zhang, RF; Guo, W; Wang, GL; Chen, XL; Li, Z; Xu, XY or concate me.

Reference:
Patent; Guizhou University; Xue Wei; Zhang Juping; Zhang Cheng; Chen Lijuan; Wang Yihui; Li Pu; Li Qin; Ruan Xianghui; Wang Xiaobin; Wu Xiaoqiong; Wang Jun; (24 pag.)CN107602493; (2019); B;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Discovery of C8H11NO

Application In Synthesis of 2-(4-Aminophenyl)ethanol. About 2-(4-Aminophenyl)ethanol, If you have any questions, you can contact Zhao, LX; Hu, CY; Cong, XF; Deng, GD; Liu, LL; Luo, MM; Zeng, XM or concate me.

Recently I am researching about SIGMA-BOND METATHESIS; CHEMOSELECTIVE HYDROGENATION; SELECTIVE HYDROGENATION; GRIGNARD-REAGENTS; SECONDARY AMIDES; CARBONYL; REDUCTION; NITROARENES; COMPLEXES; CARBENES, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21572175, 21871186, 21971168]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [20826041D4117]; Center for Computational Science and Engineering at SUSTech; SUSTech start-up fund [Y01216248]. Application In Synthesis of 2-(4-Aminophenyl)ethanol. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Zhao, LX; Hu, CY; Cong, XF; Deng, GD; Liu, LL; Luo, MM; Zeng, XM. The CAS is 104-10-9. Through research, I have a further understanding and discovery of 2-(4-Aminophenyl)ethanol

Transition metal catalysis that utilizes N-hetero-cyclic carbenes as noninnocent ligands in promoting transformations has not been well studied. We report here a cyclic (alkyl)(amino)carbene (CAAC) ligand-promoted nitro deoxyge-native hydroboration with cost-effective chromium catalysis. Using 1 mol % of CAAC-Cr precatalyst, the addition of HB-pin to nitro scaffolds leads to deoxygenation, allowing for the retention of various reducible functionalities and the compatibility of sensitive groups toward hydroboration, thereby providing a mild, chemoselective, and facile strategy to form anilines, as well as heteroaryl and aliphatic amine derivatives, with broad scope and particularly high turnover numbers (up to 1.8 X 10(6)). Mechanistic studies, based on theoretical calculations, indicate that the CAAC ligand plays an important role in promoting polarity reversal of hydride of HBpin; it serves as an H-shuttle to facilitate deoxygenative hydroboration. The preparation of several commercially available pharmaceuticals by means of this strategy highlights its potential application in medicinal chemistry.

Application In Synthesis of 2-(4-Aminophenyl)ethanol. About 2-(4-Aminophenyl)ethanol, If you have any questions, you can contact Zhao, LX; Hu, CY; Cong, XF; Deng, GD; Liu, LL; Luo, MM; Zeng, XM or concate me.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Final Thoughts on Chemistry for C8H11NO

Application In Synthesis of 2-(4-Aminophenyl)ethanol. About 2-(4-Aminophenyl)ethanol, If you have any questions, you can contact Liu, ZS; Zeng, H; Zhang, WJ; Song, C; Yang, F; Liu, Y; Zhu, J or concate me.

Recently I am researching about INDOLE SYNTHESIS; ORTHO-ACYLATION; NITROSOANILINES; BOND; POLYMERS; ACTIVATION; ARYLATION; METAL; ACIDS, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21425415, 21774056]; National Basic Research Program of ChinaNational Basic Research Program of China [2015CB856303]; Science and Technology Department of Jiangsu Province [BRA2017360, BK20181255]. Published in ELSEVIER SCI LTD in OXFORD ,Authors: Liu, ZS; Zeng, H; Zhang, WJ; Song, C; Yang, F; Liu, Y; Zhu, J. The CAS is 104-10-9. Through research, I have a further understanding and discovery of 2-(4-Aminophenyl)ethanol. Application In Synthesis of 2-(4-Aminophenyl)ethanol

Transition metal-catalyzed directed C-H functionalization promises a straightforward route to polymerization but remains highly underexplored. We report herein the development of a polymer synthesis protocol based on Rh(III)-catalyzed N-nitroso-directed C-H olefination reaction. The single bifunctional monomer approach allows the high-yield generation of polymers with relatively narrow PDI under mild conditions. Further convenient denitrosation transformation furnishes responsive fluorescent polymers with metal ion-selective quenching behaviors. The high Hg2+ selectivity observed in one system provides a handy enabling tool for detecting this hazardous species.

Application In Synthesis of 2-(4-Aminophenyl)ethanol. About 2-(4-Aminophenyl)ethanol, If you have any questions, you can contact Liu, ZS; Zeng, H; Zhang, WJ; Song, C; Yang, F; Liu, Y; Zhu, J or concate me.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

What I Wish Everyone Knew About 90-16-4

Application In Synthesis of Benzo[d][1,2,3]triazin-4(3H)-one. About Benzo[d][1,2,3]triazin-4(3H)-one, If you have any questions, you can contact El Rayes, SM; Ali, IAI; Fathalla, W; Mahmoud, MAA or concate me.

Application In Synthesis of Benzo[d][1,2,3]triazin-4(3H)-one. In 2020 ACS OMEGA published article about PHARMACOLOGICAL EVALUATION; LIGANDS; GROWTH in [El Rayes, Samir M.; Ali, Ibrahim A. I.; Mahmoud, Mostafa A. A.] Suez Canal Univ, Fac Sci, Dept Chem, Ismailia 41529, Egypt; [Fathalla, Walid] Port Said Univ, Fac Engn, Phys & Math Engn Dept, Port Said 42526, Egypt in 2020, Cited 24. The Name is Benzo[d][1,2,3]triazin-4(3H)-one. Through research, I have a further understanding and discovery of 90-16-4.

In one-pot strategy, diazotization of methyl anthranilate 5 followed by addition of amino acid ester hydrochloride, we have prepared methyl-2-(4-oxobenzotriazin-3(4H)-yl)-alkanoates 6a-c. Starting with hydrazides 7a,b, N-alkyl-2-(4-oxobenzotriazin-3(4H)-yl)-alkanamides 9-10(a-h) and methyl-2-(2-(4-oxobenzotriazin-3(4H)-yl)alkanamido)alkanoates 11- 12(a-e) were prepared via azide coupling. Hydrazones 13-15 were prepared via condensation of hydrazides 7a,b with 4-methoxybenzaldehyde, 4-dimethylaminobenzaldehyde, and/or arabinose. Molecular docking was done for synthesized compounds using MOE 2008-10 software. The compounds 9a, 12a, 12c, 13a, 13b, and 14b have the most pronounced strong binding affinities toward the target E. coli Fab-H receptor, whereas compounds 3, 11e, 12e, and 13a have the most pronounced strong binding affinities toward the target vitamin D receptor. The in vitro antibacterial activities of the highest binding affinity docked compounds were tested against E. coli, Staphylococcus aureus, and Salmonella spp. Majority of the tested compounds showed effective positive results against E. coli, while they were almost inactive against Staphylococcus aureus and Salmonella spp. The in vitro cytotoxic activities of the highest binding affinity-docked compounds were tested against the human liver carcinoma cell line (HepG2). Some compounds showed potent cytotoxic activity with low IC50 values, especially for 3 (6.525 mu M) and 13a (10.97 mu M) than that for standard drug doxorubicin (2.06 mu M).

Application In Synthesis of Benzo[d][1,2,3]triazin-4(3H)-one. About Benzo[d][1,2,3]triazin-4(3H)-one, If you have any questions, you can contact El Rayes, SM; Ali, IAI; Fathalla, W; Mahmoud, MAA or concate me.

Reference:
Patent; Guizhou University; Xue Wei; Zhang Juping; Zhang Cheng; Chen Lijuan; Wang Yihui; Li Pu; Li Qin; Ruan Xianghui; Wang Xiaobin; Wu Xiaoqiong; Wang Jun; (24 pag.)CN107602493; (2019); B;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

What Kind of Chemistry Facts Are We Going to Learn About Benzo[d][1,2,3]triazin-4(3H)-one

About Benzo[d][1,2,3]triazin-4(3H)-one, If you have any questions, you can contact Chen, XL; Zhou, Z; Li, Z; Xu, XY or concate me.. Quality Control of Benzo[d][1,2,3]triazin-4(3H)-one

Quality Control of Benzo[d][1,2,3]triazin-4(3H)-one. In 2020 PHOSPHORUS SULFUR published article about ANTICANCER; DISCOVERY; LARGAZOLE in [Chen, Xiulei; Zhou, Zhen; Li, Zhong; Xu, Xiaoyong] East China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China; [Li, Zhong; Xu, Xiaoyong] Shanghai Collaborat Innovat Ctr Biomfg Technol, Shanghai, Peoples R China in 2020, Cited 29. The Name is Benzo[d][1,2,3]triazin-4(3H)-one. Through research, I have a further understanding and discovery of 90-16-4.

A series of novel 1,2,3-benzotriazin-4-one derivatives containing 4,5-dihydrothiazole-2-thiol were synthesized and characterized by H-1 NMR, C-13 NMR, F-19 NMR and HRMS. The bioassay results showed that compounds 3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)-7-methoxybenzo[d][1-3]triazin-4(3H)-one, 3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)-6-nitrobenzo[d][1-3]triazin-4(3H)-one, 7-chloro-3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)benzo[d][1-3]triazin-4(3H)-one exhibited good control efficacy against the cucumber root-knot nematode disease caused by Meloidogyne incognita at the concentration of 10.0 mg L-1 in vivo. Compound 7-chloro-3-(3-((4,5-dihydrothiazol-2-yl)thio)propyl)benzo[d][1-3]triazin-4(3H)-one showed excellent nematicidal activity with inhibition 68.3% at a concentration of 1.0 mg L-1. It suggested that the structure of 1,2,3-benzotriazin-4-one containing 4,5-dihydro-thiazole-2-thiol could be optimized further.

About Benzo[d][1,2,3]triazin-4(3H)-one, If you have any questions, you can contact Chen, XL; Zhou, Z; Li, Z; Xu, XY or concate me.. Quality Control of Benzo[d][1,2,3]triazin-4(3H)-one

Reference:
Patent; Guizhou University; Xue Wei; Zhang Juping; Zhang Cheng; Chen Lijuan; Wang Yihui; Li Pu; Li Qin; Ruan Xianghui; Wang Xiaobin; Wu Xiaoqiong; Wang Jun; (24 pag.)CN107602493; (2019); B;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Awesome Chemistry Experiments For C7H5N3O

About Benzo[d][1,2,3]triazin-4(3H)-one, If you have any questions, you can contact Barak, DS; Mukhopadhyay, S; Dahatonde, DJ; Batra, S or concate me.. Quality Control of Benzo[d][1,2,3]triazin-4(3H)-one

An article NaNO2/I-2 as an alternative reagent for the synthesis of 1,2,3-benzotriazin-4(3H)-ones from 2-aminobenzamides WOS:000456353000009 published article about CATALYZED DENITROGENATIVE ANNULATION; TERT-BUTYL NITRITE; NEMATOCIDAL ACTIVITIES; SELECTIVE SYNTHESIS; DERIVATIVES; 1,2,3-BENZOTRIAZINE-4-(3H)-ONES; ACID in [Barak, Dinesh S.; Mukhopadhyay, Sushobhan; Dahatonde, Dipak J.; Batra, Sanjay] CSIR Cent Drug Res Inst, Med & Proc Chem Div, Sect 10,Jankipuram Extens,Sitapur Rd, Lucknow 226031, Uttar Pradesh, India; [Batra, Sanjay] CSIR HRDC, Postal Staff Coll Area, Sect 19, Ghaziabad 201002, India in 2019, Cited 39. The Name is Benzo[d][1,2,3]triazin-4(3H)-one. Through research, I have a further understanding and discovery of 90-16-4. Quality Control of Benzo[d][1,2,3]triazin-4(3H)-one

An efficient transformation of 2-aminobenzamides to 1,2,3-benzotriazin-4(3H)-ones in the presence of sodium nitrite (NaNO2) and Iodine (I-2) is described. The reaction is proposed to proceed via formation of nitrosyl halide that induces nitrosylation of the amino group of 2-aminobenzamide leading to diazotization followed by intramolecular cyclization. (C) 2018 Elsevier Ltd. All rights reserved.

About Benzo[d][1,2,3]triazin-4(3H)-one, If you have any questions, you can contact Barak, DS; Mukhopadhyay, S; Dahatonde, DJ; Batra, S or concate me.. Quality Control of Benzo[d][1,2,3]triazin-4(3H)-one

Reference:
Patent; Guizhou University; Xue Wei; Zhang Juping; Zhang Cheng; Chen Lijuan; Wang Yihui; Li Pu; Li Qin; Ruan Xianghui; Wang Xiaobin; Wu Xiaoqiong; Wang Jun; (24 pag.)CN107602493; (2019); B;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics

Archives for Chemistry Experiments of 2-(4-Aminophenyl)ethanol

About 2-(4-Aminophenyl)ethanol, If you have any questions, you can contact Bao, LX; Yu, ZB; Fei, T; Yan, ZY; ZLi, JZ; Sun, CH; Pang, SP or concate me.. HPLC of Formula: C8H11NO

HPLC of Formula: C8H11NO. Bao, LX; Yu, ZB; Fei, T; Yan, ZY; ZLi, JZ; Sun, CH; Pang, SP in [Bao, Lingxiang; Yu, Zongbao; Fei, Teng; Yan, Zhiyuan; Li, Jiazhe; Sun, Chenghui; Pang, Siping] Beijing Inst Technol, Sch Mat Sci & Engn, Beijing 100081, Peoples R China; [Sun, Chenghui; Pang, Siping] Beijing Inst Technol, Key Lab, Minist Educ High Energy Dens Mat, Beijing 100081, Peoples R China published Palladium supported on metal-organic framework as a catalyst for the hydrogenation of nitroarenes under mild conditions in 2020, Cited 42. The Name is 2-(4-Aminophenyl)ethanol. Through research, I have a further understanding and discovery of 104-10-9.

Sustainable development demands an environmentally friendly and efficient method for the hydrogenation of organic molecules, including the hydrogenation of functionalized nitroarenes. In this study, a highly active and selective metal-organic framework-supported palladium catalyst was prepared for the catalytic hydrogenation of nitroarenes. High selectivity (>99%) and excellent yield (98%) of aniline were realized after 2 hours in ethanol under hydrogen (1 atm) at room temperature. The reductions were successfully carried out in the presence of a wide range of other reducible functional groups. More importantly, the catalyst was very stable without the loss of its catalytic activity after five cycles.

About 2-(4-Aminophenyl)ethanol, If you have any questions, you can contact Bao, LX; Yu, ZB; Fei, T; Yan, ZY; ZLi, JZ; Sun, CH; Pang, SP or concate me.. HPLC of Formula: C8H11NO

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Let`s talk about compound :2-(4-Aminophenyl)ethanol

Product Details of 104-10-9. About 2-(4-Aminophenyl)ethanol, If you have any questions, you can contact Moldovan, RP; Wenzel, B; Teodoro, R; Neumann, W; Dukic-Stefanovic, S; Kraus, W; Rong, PJ; Deuther-Conrad, W; Hey-Hawkins, E; Krugel, U; Brust, P or concate me.

Product Details of 104-10-9. Recently I am researching about BINDING-SITES; P2X RECEPTORS; PURINERGIC RECEPTORS; DRUG-METABOLISM; P2Y1 RECEPTOR; IN-VIVO; ANTAGONISTS; DISCOVERY; LIGAND; RAT, Saw an article supported by the Life Science Stiftung [1011170009]; HZDR-Innovationsfonds; Sino-German Center for Research Promotion [GZ1236]; Fonds der Chemischen IndustrieFonds der Chemischen IndustrieEuropean Commission. Published in ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER in ISSY-LES-MOULINEAUX ,Authors: Moldovan, RP; Wenzel, B; Teodoro, R; Neumann, W; Dukic-Stefanovic, S; Kraus, W; Rong, PJ; Deuther-Conrad, W; Hey-Hawkins, E; Krugel, U; Brust, P. The CAS is 104-10-9. Through research, I have a further understanding and discovery of 2-(4-Aminophenyl)ethanol

Purine nucleotides such as ATP and ADP are important extracellular signaling molecules in almost all tissues activating various subtypes of purinoreceptors. In the brain, the P2Y(1) receptor (P2Y(1)R) subtype mediates trophic functions like differentiation and proliferation, and modulates fast synaptic transmission, both suggested to be affected in diseases of the central nervous system. Research on P2Y(1)R is limited because suitable brain-penetrating P2Y(1)R-selective tracers are not yet available. Here, we describe the first efforts to develop an F-18-labeled PET tracer based on the structure of the highly affine and selective, non-nucleotidic P2Y(1)R allosteric modulator 1-(2-[2-(tert-butyl)phenoxy]pyridin-3-yl)-3-[4- (trifluoromethoxy)phenyl]urea (7). A small series of fluorinated compounds was developed by systematic modification of the p-(trifluoromethoxy)phenyl, the urea and the 2-pyridyl subunits of the lead compound 7. Additionally, the p-(trifluoromethoxy)phenyl subunit was substituted by carborane, a boron-rich cluster with potential applicability in boron neutron capture therapy (BNCT). By functional assays, the new fluorinated derivative 1-{2-[2-(tert-butyl)phenoxy]pyridin-3-yl}-3-[4-(2-fluoroethyl) phenyl]urea (18) was identified with a high P2Y(1)R antagonistic potency (IC50 = 10 nM). Compound [F-18] 18 was radiosynthesized by using tetra-n-butyl ammonium [F-18]fluoride with high radiochemical purity, radiochemical yield and molar activities. Investigation of brain homogenates using hydrophilic interaction chromatography (HILIC) revealed [F-18]fluoride as major radiometabolite. Although [F-18]18 showed fast in vivo metabolization, the high potency and unique allosteric binding mode makes this class of compounds interesting for further optimizations and investigation of the theranostic potential as PET tracer and BNCT agent. (C) 2019 Elsevier Masson SAS. All rights reserved.

Product Details of 104-10-9. About 2-(4-Aminophenyl)ethanol, If you have any questions, you can contact Moldovan, RP; Wenzel, B; Teodoro, R; Neumann, W; Dukic-Stefanovic, S; Kraus, W; Rong, PJ; Deuther-Conrad, W; Hey-Hawkins, E; Krugel, U; Brust, P or concate me.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Our Top Choice Compound:104-10-9

About 2-(4-Aminophenyl)ethanol, If you have any questions, you can contact Hansa, RKC; Khan, MMK; Frangie, MM; Gilmore, DF; Shelton, RS; Savenka, AV; Basnakian, AG; Shuttleworth, SL; Smeltzer, MS; Alam, MA or concate me.. Recommanded Product: 104-10-9

In 2021.0 EUR J MED CHEM published article about STAPHYLOCOCCUS-AUREUS MRSA; ACINETOBACTER-BAUMANNII; RESISTANT; ANTIBIOTICS; INFECTIONS; PERSISTERS; INHIBITORS; GROWTH in [Hansa, Raj K. C.; Khan, M. M. K.; Frangie, M. M.; Alam, M. A.] Arkansas State Univ, Coll Sci & Math, Dept Chem & Phys, Jonesboro, AR 72467 USA; [Gilmore, D. F.] Arkansas State Univ, Coll Sci & Math, Dept Biol Sci, Jonesboro, AR 72467 USA; [Shelton, R. S.; Savenka, A., V; Basnakian, A. G.] Univ Arkansas Med Sci, Dept Pharmacol & Toxicol, 4301 W Markham St, Little Rock, AR 72205 USA; [Basnakian, A. G.] Cent Arkansas Vet Healthcare Syst, W 7th St, Little Rock, AR 72205 USA; [Shuttleworth, S. L.; Smeltzer, M. S.] Univ Arkansas Med Sci, Dept Microbiol & Immunol, Dept Orthopaed Surg, Ctr Microbial Pathogenesis & Host Inflammatory Re, 4301 W Markham, Little Rock, AR 72205 USA in 2021.0, Cited 39.0. The Name is 2-(4-Aminophenyl)ethanol. Through research, I have a further understanding and discovery of 104-10-9. Recommanded Product: 104-10-9

A collection of potent antimicrobials consisting of novel 1,3-bis-benzoic acid and trifluoromethyl phenyl derived pyrazoles has been synthesized and tested for antibacterial activity. The majority of trifluoromethyl phenyl derivatives are highly potent growth inhibitors of Gram-positive bacteria and showed low toxicity to human cultured cells. In particular, two compounds (59 and 74) were selected for additional studies. These compounds are highly effective against Staphylococcus aureus as shown by a low minimum inhibitory concentration (MIC), a bactericidal effect in time-kill assays, moderate inhibition of biofilm formation as well as biofilm destruction, and a bactericidal effect against stationary phase cells representing non-growing persister cells. Multistep resistance assays showed a very low tendency for S. aureus and Enterococcus faecalis to develop resistance through mutation. Additionally, in vivo mouse model studies showed no harmful effects at doses up to 50 mg/kg using 14 blood plasma organ toxicity markers or TUNEL assay in liver and kidney. Investigations into the mode of action by performing macromolecular synthesis inhibition studies showed a broad range of inhibitory effects, suggesting targets that have a global effect on bacterial cell function. Published by Elsevier Masson SAS.

About 2-(4-Aminophenyl)ethanol, If you have any questions, you can contact Hansa, RKC; Khan, MMK; Frangie, MM; Gilmore, DF; Shelton, RS; Savenka, AV; Basnakian, AG; Shuttleworth, SL; Smeltzer, MS; Alam, MA or concate me.. Recommanded Product: 104-10-9

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Some scientific research about C7H5N3O

COA of Formula: C7H5N3O. About Benzo[d][1,2,3]triazin-4(3H)-one, If you have any questions, you can contact El Rayes, SM; Ali, IAI; Fathalla, W; Mahmoud, MAA or concate me.

An article Synthesis and Biological Activities of Some New Benzotriazinone Derivatives Based on Molecular Docking; Promising HepG2 Liver Carcinoma Inhibitors WOS:000523299700057 published article about PHARMACOLOGICAL EVALUATION; LIGANDS; GROWTH in [El Rayes, Samir M.; Ali, Ibrahim A. I.; Mahmoud, Mostafa A. A.] Suez Canal Univ, Fac Sci, Dept Chem, Ismailia 41529, Egypt; [Fathalla, Walid] Port Said Univ, Fac Engn, Phys & Math Engn Dept, Port Said 42526, Egypt in 2020, Cited 24. The Name is Benzo[d][1,2,3]triazin-4(3H)-one. Through research, I have a further understanding and discovery of 90-16-4. COA of Formula: C7H5N3O

In one-pot strategy, diazotization of methyl anthranilate 5 followed by addition of amino acid ester hydrochloride, we have prepared methyl-2-(4-oxobenzotriazin-3(4H)-yl)-alkanoates 6a-c. Starting with hydrazides 7a,b, N-alkyl-2-(4-oxobenzotriazin-3(4H)-yl)-alkanamides 9-10(a-h) and methyl-2-(2-(4-oxobenzotriazin-3(4H)-yl)alkanamido)alkanoates 11- 12(a-e) were prepared via azide coupling. Hydrazones 13-15 were prepared via condensation of hydrazides 7a,b with 4-methoxybenzaldehyde, 4-dimethylaminobenzaldehyde, and/or arabinose. Molecular docking was done for synthesized compounds using MOE 2008-10 software. The compounds 9a, 12a, 12c, 13a, 13b, and 14b have the most pronounced strong binding affinities toward the target E. coli Fab-H receptor, whereas compounds 3, 11e, 12e, and 13a have the most pronounced strong binding affinities toward the target vitamin D receptor. The in vitro antibacterial activities of the highest binding affinity docked compounds were tested against E. coli, Staphylococcus aureus, and Salmonella spp. Majority of the tested compounds showed effective positive results against E. coli, while they were almost inactive against Staphylococcus aureus and Salmonella spp. The in vitro cytotoxic activities of the highest binding affinity-docked compounds were tested against the human liver carcinoma cell line (HepG2). Some compounds showed potent cytotoxic activity with low IC50 values, especially for 3 (6.525 mu M) and 13a (10.97 mu M) than that for standard drug doxorubicin (2.06 mu M).

COA of Formula: C7H5N3O. About Benzo[d][1,2,3]triazin-4(3H)-one, If you have any questions, you can contact El Rayes, SM; Ali, IAI; Fathalla, W; Mahmoud, MAA or concate me.

Reference:
Patent; Guizhou University; Xue Wei; Zhang Juping; Zhang Cheng; Chen Lijuan; Wang Yihui; Li Pu; Li Qin; Ruan Xianghui; Wang Xiaobin; Wu Xiaoqiong; Wang Jun; (24 pag.)CN107602493; (2019); B;,
Amide – Wikipedia,
Amide – an overview | ScienceDirect Topics