Tag: M.W=150-200

An article Diboronic Acid Anhydrides as Effective Catalysts for the Hydroxy-Directed Dehydrative Amidation of Carboxylic Acids WOS:000471212100091 published article about DIRECT AMIDE FORMATION; MECHANISTIC INSIGHTS; BOND FORMATION; BORONIC ACIDS; CONDENSATION; ALPHA; CYCLOADDITIONS; ACTIVATION; CHEMISTRY; AMINES in [Shimada, Naoyuki] Kitasato Univ, Dept Pharmaceut Sci, Lab Organ Chem Drug Dev, Tokyo 1088641, Japan; Kitasato Univ, Dept Pharmaceut Sci, Med Res Labs, Tokyo 1088641, Japan in 2019.0, Cited 72.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. HPLC of Formula: C13H13N

The direct catalytic dehydrative amidation of beta-hydroxycarboxylic acids with amines is described. A biphenyl-based diboronic acid anhydride with a B-O-B skeleton is shown to be an exceptionally effective catalyst for the reaction, providing beta-hydroxycarboxylic amides in high to excellent yields with a low catalyst loading (minimum of 0.01 mol %, TON up to 7,500). This hydroxy-directed amidation shows excellent chemoselectivity and is applicable to gram-scale drug synthesis.

HPLC of Formula: C13H13N. Welcome to talk about 91-00-9, If you have any questions, you can contact Shimada, N; Hirata, M; Koshizuka, M; Ohse, N; Kaito, R; Makino, K or send Email.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

HPLC of Formula: C13H13N. In 2020.0 PAK J PHARM SCI published article about SUCCINAMIC ACID; 1,4-DITHIINS; BINDING; ESTER in [Ahme, Sumbul; Perveen, Shahnaz] Pakistan Council Sci & Ind Res, Labs Complex, Karachi 75280, Pakistan; [Perveen, Shahnaz; Khan, Khalid Mohammed; Naz, Farzana] Univ Karachi, Int Ctr Chem & Biol Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan; [Ali, Rahat Azher] Univ Karachi, Dept Chem, Karachi 75270, Pakistan; [Ajaz, Munazza; Shah, Samreen] Fed Urdu Univ Arts Sci & Technol, Dept Chem, Univ Rd,Gulshan E Iqbal Campus, Karachi, Pakistan; [Khan, Khalid Mohammed] Imam Abdulrahman Bin Faisal Univ, Inst Res & Med Consultat IRMC, Dept Clin Pharm, Dammam, Saudi Arabia in 2020.0, Cited 28.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Sixteen derivatives of dithiin diisoimide 2a-2p have been synthesized and screened for antibacterial and antifungal activity. Compounds 2a-2g and 2i-2p are almost same or more active than gentamicine against Acinetobacter. Whereby compound 2,6-didodecyl-1H,5H-pyrrolo[3′,4′,5,6][1,4]dithiino[2,3-c]pyrrole-1,3,5,7(2H,6H)-tetrone (2d) having zone of inhibition 20 mm against Acinetobacter is the most potent among all these compounds and can be used as lead compound for the treatment of Acinetobacter infection.

Welcome to talk about 91-00-9, If you have any questions, you can contact Ahme, S; Perveen, S; Khan, KM; Naz, F; Ali, RA; Ajaz, M; Shah, S or send Email.. HPLC of Formula: C13H13N

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Development and mechanistic investigation of the manganese(iii) salen-catalyzed dehydrogenation of alcohols WOS:000457342200020 published article about TRANSFER HYDROGENATION; SUBSTITUENT CONSTANTS; SUSTAINABLE SYNTHESIS; AMINES; LIGAND; KETONES; IRON; EPOXIDATION; ALKYLATION; EFFICIENT in [Samuelsen, SimoneV.; Santilli, Carola; Madsen, Robert] Tech Univ Denmark, Dept Chem, DK-2800 Lyngby, Denmark; [Ahlquist, Marten S. G.] KTH Royal Inst Technol, Dept Theoret Chem & Biol, Sch Engn Sci Chem Biotechnol & Hlth, S-10691 Stockholm, Sweden in 2019.0, Cited 64.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. Quality Control of Diphenylmethanamine

The first example of a manganese(III) catalyst for the acceptorless dehydrogenation of alcohols is presented. N,N’-Bis(salicylidene)-1,2-cyclohexanediaminomanganese(III) chloride (2) has been shown to catalyze the direct synthesis of imines from a variety of alcohols and amines with the liberation of hydrogen gas. The mechanism has been investigated experimentally with labelled substrates and theoretically with DFT calculations. The results indicate a metal-ligand bifunctional pathway in which both imine groups in the salen ligand are first reduced to form a manganese(III) amido complex as the catalytically active species. Dehydrogenation of the alcohol then takes place by a stepwise outer-sphere hydrogen transfer generating a manganese(III) salan hydride from which hydrogen gas is released.

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Improving C=N Bond Reductions with (Cyclopentadienone)iron Complexes: Scope and Limitations published in 2019.0. Formula: C13H13N, Reprint Addresses Pignataro, L; Gennari, C (corresponding author), Univ Milan, Dipartimento Chim, Via C Golgi 19, I-20133 Milan, Italy.; Piarulli, U (corresponding author), Univ Insubria, Dipartimento Sci & Alta Tecnol, Via Valleggio 11, I-22100 Como, Italy.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

Herein, we broaden the application scope of (cyclopentadienone)iron complexes 1 in C=N bond reduction. The catalytic scope of pre-catalyst 1b, which is more active than the Knolker complex (1a) and other members of its family, has been expanded to the catalytic transfer hydrogenation (CTH) of a wider range of aldimines and ketimines, either pre-isolated or generated in situ. The kinetics of 1b-promoted CTH of ketimine S1 were assessed, showing a pseudo-first order profile, with TOF = 6.07 h(-1) at 50 % conversion. Moreover, the chiral complex 1c and its analog 1d were employed in the enantioselective reduction of ketimines and reductive amination of ketones, giving fair to good yields and moderate enantioselectivity.

Formula: C13H13N. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Synthesis of New 1,3,5-Azadiphosphorinanes Based on Aliphatic Amines WOS:000522647800009 published article about CYCLIC AMINOMETHYLPHOSPHINES; COMPLEXES in [Musina, E. I.; Musin, L. I.; Litvinov, I. A.; Karasik, A. A.] Russian Acad Sci, Kazan Sci Ctr, Fed Res Ctr, AE Arbuzov Inst Organ & Phys Chem, Kazan 420088, Russia in 2020.0, Cited 25.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. Category: amides-buliding-blocks

New 1-aza-3,5-diphosphorinanes have been synthesized as a mixture of RR/SS- and RS-isomers via the reaction of bis(phenylphosphanyl)methane, paraformaldehyde, isopropylamine, of benzhydrylamine.

Category: amides-buliding-blocks. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Total synthesis of Met(10)-teixobactin published in 2019.0. Quality Control of Diphenylmethanamine, Reprint Addresses Reddy, DS (corresponding author), CSIR Natl Chem Lab, Organ Chem Div, Dr Homi Bhabha Rd, Pune 411008, Maharashtra, India.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

The total synthesis of cyclic depsipeptide Met(10)-teixobactin in solution-phase is described. Teixobactin is a structurally and mechanistically novel antimicrobial peptidic natural product with very impressive activities against Gram-positive pathogens. It happens to possess an L-allo-enduracididine (End) residue as part of macrocyclic ring which is not readily accessible. In this report, we have used serine ligation strategy as the key step to prepare an analogue of teixobactin where End being replaced with a readily available amino acid methionine. (C) 2019 Elsevier Ltd. All rights reserved.

Welcome to talk about 91-00-9, If you have any questions, you can contact Gunjal, VB; Reddy, DS or send Email.. Quality Control of Diphenylmethanamine

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Recommanded Product: 91-00-9. Recently I am researching about ASYMMETRIC-SYNTHESIS; HYDROPHOSPHONYLATION; AMINALIZATION; IMINES; ACID, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [51373067]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Liu, YX; Wang, JD; Wei, ZL; Cao, JG; Liang, DP; Lin, YJ; Duan, HF. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

N,N’-Acetals are sensitive compounds, and the challenging asymmetric synthesis of acyclic N,N’-acetals by the general addition of amines to ketimines has never been reported so far. In this study, highly enantioselective addition of aryl amines to isatin-derived ketimines catalyzed by chiral urea derived from quinine was developed. A series of new acyclic N,N’-acetals were constructed by this protocol in high to excellent yields (78-99%) and high to excellent enantioselectivities (76-96% ee).

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Chemical profiling of HIV-1 capsid-targeting antiviral PF74 WOS:000546723400025 published article about THERMAL SHIFT ASSAYS; CYCLOPHILIN-A; REPLICATION; INFECTION; PROTEIN; ROLES; INHIBITION; DISCOVERY; POTENT; CELLS in [Wang, Lei; Vernekar, Sanjeev Kumar V.; Do, Ha T.; Sahani, Rajkumar Lalji; Xie, Jiashu; Wang, Zhengqiang] Univ Minnesota, Coll Pharm, Ctr Drug Design, Minneapolis, MN 55455 USA; [Casey, Mary C.] Univ Missouri, Christopher S Bond Life Sci Ctr, Dept Mol Microbiol & Immunol, Sch Med, Columbia, MO 65211 USA; [Kirby, Karen A.; Du, Haijuan; Zhang, Huanchun; Tedbury, Philip R.; Sarafianos, Stefan G.] Emory Univ, Dept Pediat, Lab Biochem Pharmacol, Sch Med, Atlanta, GA 30322 USA; [Hachiya, Atsuko] Natl Hosp Org, Clin Res Ctr, Nagoya Med Ctr, Nagoya, Aichi 4600001, Japan; [Wang, Lei] Dalian Univ Technol, Sch Chem Engn, Dept Pharm, Dalian 116024, Peoples R China in 2020.0, Cited 51.0. COA of Formula: C13H13N. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

The capsid protein (CA) of HIV-1 plays essential roles in multiple steps of the viral replication cycle by assembling into functional capsid core, controlling the kinetics of uncoating and nuclear entry, and interacting with various host factors. Targeting CA represents an attractive yet underexplored antiviral approach. Of all known CA-targeting small molecule chemotypes, the peptidomimetic PF74 is particularly interesting because it binds to the same pocket used by a few important host factors, resulting in highly desirable antiviral phenotypes. However, further development of PF74 entails understanding its pharmacophore and mitigating its poor metabolic stability. We report herein the design, synthesis, and evaluation of a large number of PF74 analogs aiming to provide a comprehensive chemical profiling of PF74 and advance the understanding on its detailed binding mechanism and pharmacophore. The analogs, containing structural variations mainly in the aniline domain and/or the indole domain, were assayed for their effect on stability of CA hexamers, antiviral activity, and cytotoxicity. Selected analogs were also tested for metabolic stability in liver microsomes, alone or in the presence of a CYP3A inhibitor. Collectively, our studies identified important pharmacophore elements and revealed additional binding features of PF74, which could aid in future design of improved ligands to better probe the molecular basis of CA-host factor interactions, design strategies to disrupt them, and ultimately identify viable CA-targeting antiviral leads. (C) 2020 Elsevier Masson SAS. All rights reserved.

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Product Details of 91-00-9. Recently I am researching about SULFOXONIUM YLIDES; BOND ACTIVATION; RH(III)-CATALYZED SYNTHESIS; ORGANIC-SYNTHESIS; DIAZO-COMPOUNDS; PRIMARY AMINES; BENZYLAMINES; ANNULATION; ALKYNES; FUNCTIONALIZATION, Saw an article supported by the NSFCNational Natural Science Foundation of China (NSFC) [81373259, 81573286, 81602954]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Nie, RF; Lai, RZ; Lv, SY; Xu, YY; Guo, L; Wang, QT; Wu, Y. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

A water-mediated C-H activation using sulfoxonium ylides is reported, providing a general, green and step-economic approach to construct a C-C bond and varieties of useful N-heterocycle scaffolds. Notably, the water-mediated activation, in contrast to that in organic solvents, shows great potential in pharmaceutical, biochemistry and chemical industries.

Product Details of 91-00-9. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Recommanded Product: Diphenylmethanamine. Peng, K; Luo, Q; Zhang, YC; Xia, JB in [Peng, Kai; Luo, Qi; Zhang, Yichi; Xia, Jiangbin] Wuhan Univ, Coll Chem & Mol Sci, Hubei Key Lab Organ & Polymer Optoelect Mat, Wuhan 430072, Peoples R China; [Xia, Jiangbin] Wuhan Univ, Coll Chem & Mol Sci, Minist Educ, Engn Res Ctr Organosilicon Cpds & Mat, Wuhan 430072, Peoples R China published Novel synthesis of poly(3,4-dinitro-thiophen-2-yl arylamine) derivatives via facile C-Br/N-H bulk polycondensation and its application of thermalsensor in 2020.0, Cited 42.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

C-Br/N-H bulk polycondensation is firstly proposed and corresponding poly(3,4-dinitm-thiophen-2-yl aryl-amine)s derivatives have been successfully obtained with quantitative yield. Typical crystal analysis reveals that its effective reaction points distance (RPD, distance between Br and H atom) is 5.083 angstrom, which is 66.7% longer than the sum of van der Waals radius (r(w)) of bromine and hydrogen atoms (3.05 angstrom). Carbazole-based monomer was explored as a thermalsensor with excellent relative sensitivity (S-a) of 0.45% K-1.

Recommanded Product: Diphenylmethanamine. Welcome to talk about 91-00-9, If you have any questions, you can contact Peng, K; Luo, Q; Zhang, YC; Xia, JB or send Email.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics