Tag: M.W=150-200

Sevov, Christo S. published the artcileEvolutionary Design of Low Molecular Weight Organic Anolyte Materials for Applications in Nonaqueous Redox Flow Batteries, Product Details of C10H14N2O, the publication is Journal of the American Chemical Society (2015), 137(45), 14465-14472, database is CAplus and MEDLINE.

The integration of renewable energy sources into the elec. grid requires low-cost energy storage systems that mediate the variable and intermittent flux of energy associated with most renewables. Nonaqueous redox-flow batteries have emerged as a promising technol. for grid-scale energy storage applications. Because the cost of the system scales with mass, the electroactive materials must have a low equivalent weight (ideally 150 g/(mol·e^–) or less), and must function with low mol. weight supporting electrolytes such as LiBF₄. However, soluble anolyte materials that undergo reversible redox processes in the presence of Li-ion supports are rare. We report the evolutionary design of a series of pyridine-based anolyte materials that exhibit up to two reversible redox couples at low potentials in the presence of Li-ion supporting electrolytes. A combination of cyclic voltammetry of anolyte candidates and independent synthesis of their corresponding charged-states was performed to rapidly screen for the most promising candidates. Results of this workflow provided evidence for possible decomposition pathways of first-generation materials and guided synthetic modifications to improve the stability of anolyte materials under the targeted conditions. This iterative process led to the identification of a promising anolyte material, N-Me 4-acetylpyridinium tetrafluoroborate. This compound is soluble in nonaqueous solvents, is prepared in a single synthetic step, has a low equivalent weight of 111 g/(mol·e^–), and undergoes two reversible 1e^– reductions in the presence of LiBF₄ to form reduced products that are stable over days in solution

Journal of the American Chemical Society published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C3H8N2S, Product Details of C10H14N2O.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Bromilow, John published the artcileCarbon-13 substituent chemical shifts in the side-chain carbons of aromatic systems: the importance of π-polarization in determining chemical shifts, Name: 3-Methoxybenzothioamide, the publication is Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) (1981), 753-9, database is CAplus.

¹³C substituent chem. shifts of the CO sites in the side chains of two-hundred and four m– and p-substituted benzenes were measured using a dual substituent parameter LFER, which showed that inductive effects are predominant. The reverse inductive contribution observed is explained in terms of a π-polarization mechanism. Critical support for this mechanism was obtained from an addnl. series where the CO group was complexed with Lewis acids. The concepts of extended and localized π-polarization are discussed.

Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) published new progress about 64559-06-4. 64559-06-4 belongs to amides-buliding-blocks, auxiliary class Amine,Benzene,Amide,Ether, name is 3-Methoxybenzothioamide, and the molecular formula is C8H9NOS, Name: 3-Methoxybenzothioamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Epsztajn, J. published the artcileApplication of organolithium and related reagents in synthesis. Part XII. Synthesis of phenyl- and pyridylpyridopyridazinones and their derivatives, Formula: C10H14N2O, the publication is Monatshefte fuer Chemie (1993), 124(5), 549-58, database is CAplus.

The pyridazinones I (R = 2-pyridyl, Ph), II (R = 3-pyridyl, Ph) and III (R = 4-pyridyl, Ph) were prepared from ketoamides, e.g. 4-benzoyl-N,N-diisopropyl-3-pyridinecarboxamide (IV) and 3-benzoyl-N,N-diisopropyl-4-pyridinecarboxamide (V), and hydrazine hydrate. From ketoamides IV and V in addition to the expected pyridopyridazinones II (R = Ph) and III (R = Ph) also aminopyridopyridazines VI and VII were formed. The pyridopyridazinones were alkylated with alkyl iodides.

Monatshefte fuer Chemie published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H14N2O, Formula: C10H14N2O.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Epsztajn, Jan published the artcileApplications of organolithium and related reagents in synthesis. Part 4. A general study of the reactions of N,N-dialkylpyridinecarboxamides with lithium diisopropylamide, Safety of N,N-Diethylisonicotinamide, the publication is Journal of Chemical Research, Synopses (1986), 18-19, database is CAplus.

Treatment of N,N-diisopropylpyridinecarboxamides with (Me₂CH)₂NLi (I) gave the corresponding lithiated amides regioselectively and reversibly. The lithiated amides were stable at -78°, but underwent self-addition to the parent compounds at higher temperatures and underwent trapping by a variety of carbonyl electrophiles to give a range of substituted products. E.g., treatment of N,N-diisopropylnicotinamide with I in Et₂O-C₆H₆ at -78° for 1 h, followed by addition of BzNMe₂ and stirring 2 h, gave 73% 4-benzoyl-N,N-diisopropylnicotinamide.

Journal of Chemical Research, Synopses published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C10H14N2O, Safety of N,N-Diethylisonicotinamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Wan, Lingzi published the artcileNew synthetic method of Saflufenacil, Application of N-Methyl-N-isopropylsulfamoyl amide, the publication is Huaxue Tongbao (2019), 82(9), 826-830, database is CAplus.

The synthetic process of Saflufenacil and its key intermediates is designed and completed, which has the potential for industrial manufacturing The key intermediate N-methyl-N-isopropylaminosulfonamide is prepared by using chlorosulfonyl isocyanate, t-butanol, N-methyl-N-isopropylamine as the starting material. The overall yield of the three-step reaction is about 75%. Then, 2-chloro-4-fluorobenzoic acid was used as a raw material to prepare Saflufenacil by nitration, chloridization, condensation, catalytic hydrogenation reduction, aminolysis and methylation reactions. The total yield of 8 steps is 48.6%, and the purity of the target product is 98.6%. The final products and the intermediates are characterized by NMR and MS.

Huaxue Tongbao published new progress about 372136-76-0. 372136-76-0 belongs to amides-buliding-blocks, auxiliary class Sulfamide,Amine,Aliphatic hydrocarbon chain, name is N-Methyl-N-isopropylsulfamoyl amide, and the molecular formula is C15H14Cl2S2, Application of N-Methyl-N-isopropylsulfamoyl amide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Gonzalez-Liste, Pedro J. published the artcileCatalytic Rearrangement of Aldoximes to Primary Amides in Environmentally Friendly Media under Thermal and Microwave Heating: Another Application of the Bis(allyl)-Ruthenium(IV) Dimer [{RuCl(μ-Cl)(η³:η³-C₁₀H₁₆)}₂], Application In Synthesis of 2447-79-2, the publication is ACS Sustainable Chemistry & Engineering (2015), 3(11), 3004-3011, database is CAplus.

The rearrangement of aldoximes to primary amides has been studied using the com. available bis(allyl)-ruthenium(IV) complex [{RuCl(μ-Cl)(η³:η³-C₁₀H₁₆)}₂] (1; C₁₀H₁₆ = 2,7-dimethylocta-2,6-diene-1,8-diyl) as a catalyst under thermal and microwave heating. The reactions proceeded cleanly in a mixture of water/glycerol (1:1) at 120-150°, without the assistance of any cocatalyst, affording the desired amides in moderate to high yields and short times. The process was operative with aromatic, heteroaromatic, aliphatic, and α,β-unsaturated aldoximes and tolerated the presence of several functional groups in the substrates. In addition, the recyclability of catalyst 1 (up to six consecutive runs) could be demonstrated.

ACS Sustainable Chemistry & Engineering published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H5Cl2NO, Application In Synthesis of 2447-79-2.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Li, Ze-lin published the artcilePd/Ni catalyzed selective N-H/C-H methylation of amides by using peroxides as the methylating reagents via a radical process, COA of Formula: C7H8FNO2S, the publication is Organic Chemistry Frontiers (2017), 4(11), 2207-2210, database is CAplus.

A palladium/nickel catalyzed selective N-H/C-H methylation of amides such as benzenesulfonamide, nicotinamide, benzamide, etc. by using peroxides to provide N-methylation products such as N-methylbenzenesulfonamide, N-methylnicotinamide, N-methylbenzamide, etc. and C-methylation products such as 2-methylbenzenesulfonamide, 2-methylnicotinamide, 2-methylbenzamide, etc. in moderate to good yields was described. In this procedure, peroxides play a dual role, serving as both the Me source and radical initiator. This protocol tolerated a broad range of substrates, not only various sulfonamides but also methanamides. Mechanistic investigations involving a radical process are also described.

Organic Chemistry Frontiers published new progress about 489-17-8. 489-17-8 belongs to amides-buliding-blocks, auxiliary class Fluoride,Sulfamide,Amine,Benzene, name is 4-Fluoro-2-methylbenzenesulfonamide, and the molecular formula is C7H8FNO2S, COA of Formula: C7H8FNO2S.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Blencowe, Anton published the artcileSynthesis of hyperbranched poly(aryl ether)s via carbene insertion processes, Category: amides-buliding-blocks, the publication is Macromolecules (2007), 40(4), 939-949, database is CAplus.

Homopolymerization of alkylaryl carbenes derived from diazirine monomers that featured benzyl alc. or phenol residues was found to lead to the production of soluble hyperbranched poly(aryl ether)s. The polymerization process was influenced by the solvents employed, monomer concentration, and the reaction time. An increase in the monomer concentration and reaction time was found to lead to an increase in the mol. weight characteristics of the resulting polymers as determined by gel permeation chromatog. (GPC). The composition and architecture of the polyethers were determined by NMR spectroscopic anal. and were found to be highly complex and dependent on the structure of the monomers used. All of the polymers were found to contain ether linkages formed via carbene insertion into O-H bonds, although polymers derived from phenolic carbenes also contained linkages arising from C-alkylation.

Macromolecules published new progress about 360-92-9. 360-92-9 belongs to amides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Amine,Aliphatic hydrocarbon chain,Amide, name is N,N-Diethyl-2,2,2-trifluoroacetamide, and the molecular formula is C6H10F3NO, Category: amides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Wentrup, Gerhard Juergen published the artcile1,2-Dithiacyclopentenes, XXXII. Reactions of 3H-1,2-dithiole-3-thiones with N-chlorobenzamides, Name: 2,4-Dichlorobenzamide, the publication is Justus Liebigs Annalen der Chemie (1978), 387-97, database is CAplus.

5-Phenyl-3H-1,2-dithiole-3-thione (I) reacted with RCONCl₂ [R = 2-O₂NC₆H₄, 2,4-(O₂N)ClC₆H₃, 2,4- and 2,6-Cl₂C₆H₃] to give II (R as above, R¹ = H, Cl) whereas reaction of I with RCONHCl (R as above) gave III, which, on extrusion of S gave II (R¹ = H).

Justus Liebigs Annalen der Chemie published new progress about 2447-79-2. 2447-79-2 belongs to amides-buliding-blocks, auxiliary class Chloride,Amine,Benzene,Amide, name is 2,4-Dichlorobenzamide, and the molecular formula is C7H8BFO2, Name: 2,4-Dichlorobenzamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics

Yang, Long published the artcileElectrochemical B-H Nitrogenation: Access to Amino Acid and BODIPY-Labeled nido-Carboranes, Name: N,N-Diethylisonicotinamide, the publication is Angewandte Chemie, International Edition (2021), 60(3), 1482-1487, database is CAplus and MEDLINE.

Electrocatalyzed oxidative B-H nitrogenations of nido-carborane (nido-7,8-C₂B₉H₁₂^–) with N-heterocycles have been established, enabling the preparation of various N-substituted nido-carboranes without chem. oxidants or metal catalyst under ambient conditions. The electrolysis manifold occurred with high levels of efficiency as well as chemo- and position- selectivity, employing sustainable electricity as the sole oxidant. The strategy set the stage for a user-friendly access to novel amino acid and fluorogenic boron-dipyrrin (BODIPY)-labeled nido-carborane hybrids.

Angewandte Chemie, International Edition published new progress about 530-40-5. 530-40-5 belongs to amides-buliding-blocks, auxiliary class Pyridine,Amine,Amide, name is N,N-Diethylisonicotinamide, and the molecular formula is C9H5ClO4S, Name: N,N-Diethylisonicotinamide.

Referemce:
https://en.wikipedia.org/wiki/Amide,
Amide – an overview | ScienceDirect Topics