Tag: M.W=150-200

In 2020.0 PAK J PHARM SCI published article about SUCCINAMIC ACID; 1,4-DITHIINS; BINDING; ESTER in [Ahme, Sumbul; Perveen, Shahnaz] Pakistan Council Sci & Ind Res, Labs Complex, Karachi 75280, Pakistan; [Perveen, Shahnaz; Khan, Khalid Mohammed; Naz, Farzana] Univ Karachi, Int Ctr Chem & Biol Sci, HEJ Res Inst Chem, Karachi 75270, Pakistan; [Ali, Rahat Azher] Univ Karachi, Dept Chem, Karachi 75270, Pakistan; [Ajaz, Munazza; Shah, Samreen] Fed Urdu Univ Arts Sci & Technol, Dept Chem, Univ Rd,Gulshan E Iqbal Campus, Karachi, Pakistan; [Khan, Khalid Mohammed] Imam Abdulrahman Bin Faisal Univ, Inst Res & Med Consultat IRMC, Dept Clin Pharm, Dammam, Saudi Arabia in 2020.0, Cited 28.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. SDS of cas: 91-00-9

Sixteen derivatives of dithiin diisoimide 2a-2p have been synthesized and screened for antibacterial and antifungal activity. Compounds 2a-2g and 2i-2p are almost same or more active than gentamicine against Acinetobacter. Whereby compound 2,6-didodecyl-1H,5H-pyrrolo[3′,4′,5,6][1,4]dithiino[2,3-c]pyrrole-1,3,5,7(2H,6H)-tetrone (2d) having zone of inhibition 20 mm against Acinetobacter is the most potent among all these compounds and can be used as lead compound for the treatment of Acinetobacter infection.

SDS of cas: 91-00-9. Welcome to talk about 91-00-9, If you have any questions, you can contact Ahme, S; Perveen, S; Khan, KM; Naz, F; Ali, RA; Ajaz, M; Shah, S or send Email.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Formula: C13H13N. I found the field of Chemistry very interesting. Saw the article Mild Iridium-Catalysed Isomerization of Epoxides. Computational Insights and Application to the Synthesis of beta-Alkyl Amines published in 2019.0, Reprint Addresses Verdaguer, X; Riera, A (corresponding author), Inst Res Biomed IRB Barcelona, Baldiri Reixac 10, Barcelona 08028, Spain.; Verdaguer, X; Riera, A (corresponding author), Univ Barcelona, Dept Quim Inorgan & Organ, Seccio Organ, Marti i Franques 1, E-08028 Barcelona, Spain.; Lledos, A (corresponding author), Univ Autonoma Barcelona, Dept Quim, Edifici Cn, Cerdanyola Del Valles 08193, Spain.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine.

The isomerization of epoxides to aldehydes using the readily available Crabtree’s reagent is described. The aldehydes were transformed into synthetically useful amines by a one-pot reductive amination using pyrrolidine as imine-formation catalyst. The reactions worked with low catalyst loadings in very mild conditions. The procedure is operationally simple and tolerates a wide range of functional groups. A DFT study of its mechanism is presented showing that the isomerization takes place via an iridium hydride mechanism with a low energy barrier, in agreement with the mild reaction conditions.

Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.. Formula: C13H13N

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Synthesis and crystal structure of phosphonic acid and bisphosphoramidate derivatives: QSAR studies of their anti-fungal potential on Macrophomina Phaseolina (Tassi) Goid WOS:000604177100003 published article about SIMILARITY/DIVERSITY ANALYSIS; MOLECULAR DESCRIPTORS; GETAWAY DESCRIPTORS; PREDICTION; DOCKING; INDEXES; ASSAY; RICE in [Gholivand, Khodayar; Barzegar, Omolbanin; Nasrollah Tabar, Hadis; Yaghoubi, Rouhollah; Hosseini, Mahdieh; Rahimzadeh Dashtaki, Maryam; Mani-Varnosfaderani, Ahmad] Tarbiat Modares Univ, Dept Chem, Fac Basic Sci, POB 14115-175, Tehran, Iran; [Abbod, Mohsen; Safaie, Naser] Tarbiat Modares Univ, Fac Agr, Dept Plant Pathol, Tehran, Iran; [Ebrahimi Valmoozi, Ali Asghar] Imam Hossein Univ, Dept Adv Mat, Tech Engn Fac, Tehran, Iran; [Dusek, Michal] ASCR, Vvi, Inst Phys, Slovance 2, Prague 18221 8, Czech Republic in 2021.0, Cited 51.0. HPLC of Formula: C13H13N. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

A series of phosphonic acid and bisphosphoramidate derivatives were synthesized and characterized. The bioactivities against the fungal pathogen Macrophomina phaseolina and human acetylcholinesterase AChE enzyme were studied using QSAR based on multiple linear regression. L17, with (p-Cl-C6H4-NH) (p-Cl-C6H4)C(H)P(O)(OC2H5)(2) skeleton, demonstrated a great mortality on the M. phaseolina mycelial growth by 83% inhibition at 150 mg/L; the other tested derivative showed moderate to weak antifungal activity against the fungus. QSAR model based on the GA-MLR method revealed the importance of 3D descriptors (De, Mor18e, H8m, and Mor30p) on the antifungal activity. It showed good capability in predicting the fungicidal activity of the studied molecules. Another derivative, L5, with (m-CH3-NC5H4-NH)(m-CH3-C6H4)C(H)P(O)(OCH3)(2) skeleton displays the most potent anti-AChE activity. The electronic parameters, Delta EL-H, and E-LUMO, have the highest contribution of human AChE. The authors suggest that these models could be usefully employed in designing more effective crop protection compounds without side effects on non-target organisms.

HPLC of Formula: C13H13N. Welcome to talk about 91-00-9, If you have any questions, you can contact Gholivand, K; Abbod, M; Valmoozi, AAE; Barzegar, O; Tabar, HN; Yaghoubi, R; Hosseini, M; Safaie, N; Dashtaki, MR; Dusek, M; Mani-Varnosfaderani, A or send Email.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Xie, C; Song, JL; Wu, HR; Hu, Y; Liu, HZ; Zhang, ZR; Zhang, P; Chen, BF; Han, BX in [Xie, Chao; Song, Jinliang; Wu, Haoran; Hu, Yue; Liu, Huizhen; Zhang, Zhanrong; Zhang, Pei; Chen, Bingfeng; Han, Buxing] Chinese Acad Sci, Inst Chem, CAS Res Educ Ctr Excellence Mol Sci, Beijing Natl Lab Mol Sci,CAS Key Lab Colloid & In, Beijing 100190, Peoples R China; [Xie, Chao; Wu, Haoran; Hu, Yue; Liu, Huizhen; Han, Buxing] Univ Chinese Acad Sci, Sch Chem & Chem Engn, Beijing 100049, Peoples R China published Ambient Reductive Amination of Levulinic Acid to Pyrrolidones over Pt Nanocatalysts on Porous TiO2 Nanosheets in 2019.0, Cited 50.0. Recommanded Product: 91-00-9. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Construction of N-substituted pyrrolidones from biomass-derived levulinic acid (LA) via reductive amination is a highly attractive route for biomass valorization. However, realizing this transformation using H-2 as the hydrogen source under mild conditions is still very challenging. Herein, we designed porous TiO2 nanosheets-supported Pt nanoparticles (Pt/P-TiO2) as the heterogeneous catalyst. The prepared Pt/P-TiO2 was highly efficient for reductive amination of LA to produce various N-substituted pyrrolidones (34 examples) at ambient temperature and H-2 pressure. Meanwhile, Pt/P-TiO2 showed good applicability for reductive amination of levulinic esters, 4-acetylbutyric acid, 2-acetylbenzoic acid, and 2-carboxybenzaldehyde. Systematic studies indicated that the strong acidity of P-TiO2 and the lower electron density of the Pt sites as well as the porous structure resulted in the excellent activity of Pt/P-TiO2.

Recommanded Product: 91-00-9. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Li, ML; Yu, JH; Li, YH; Zhu, SF; Zhou, QL in [Zhu, Shou-Fei; Zhou, Qi-Lin] Nankai Univ, Coll Chem, State Key Lab, Tianjin 300071, Peoples R China; Nankai Univ, Coll Chem, Inst Elementoorgan Chem, Tianjin 300071, Peoples R China published Highly enantioselective carbene insertion into N-H bonds of aliphatic amines in 2019, Cited 67. Formula: C13H13N. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Aliphatic amines strongly coordinate, and therefore easily inhibit, the activity of transition-metal catalysts, posing a marked challenge to nitrogen-hydrogen (N-H) insertion reactions. Here, we report highly enantioselective carbene insertion into N-H bonds of aliphatic amines using two catalysts in tandem: an achiral copper complex and chiral amino-thiourea. Coordination by a homoscorpionate ligand protects the copper center that activates the carbene precursor. The chiral amino-thiourea catalyst then promotes enantioselective proton transfer to generate the stereocenter of the insertion product. This reaction couples a wide variety of diazo esters and amines to produce chiral alpha-alkyl alpha-amino acid derivatives.

Welcome to talk about 91-00-9, If you have any questions, you can contact Li, ML; Yu, JH; Li, YH; Zhu, SF; Zhou, QL or send Email.. Formula: C13H13N

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Position of lipidation influences anticancer activity of Smac analogs WOS:000468145300016 published article about APOPTOSIS PROTEINS IAPS; HUMAN SERUM-ALBUMIN; X-LINKED INHIBITOR; STRUCTURAL BASIS; CELL-DEATH; REVERSIBLE LIPIDIZATION; CASPASE INHIBITION; POTENT ANTAGONISTS; TUMOR-REGRESSION; BIR DOMAINS in [Micewicz, Ewa D.; Nguyen, Christine; McBrid, William H.] Univ Calif Los Angeles, Dept Radiat Oncol, 10833 Le Conte Ave, Los Angeles, CA 90095 USA; [Micewicz, Alina] Univ Calif Los Angeles, David Geffen Sch Med, Volunteering Program, 10833 Le Conte Ave, Los Angeles, CA 90095 USA; [Waring, Alan J.] Harbor UCLA Med Ctr, Dept Med, Los Angeles Biomed Res Inst, 1000 West Carson St, Torrance, CA 90502 USA; [Ruchala, Piotr] Univ Calif Los Angeles, Dept Psychiat & Biobehav Sci, 760 Westwood Plaza, Los Angeles, CA 90024 USA; [Ruchala, Piotr] Jane & Terry Semel Inst Neurosci & Human Behav, Pasarow Mass Spectrometry Lab, 760 Westwood Plaza, Los Angeles, CA 90024 USA in 2019.0, Cited 79.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. Quality Control of Diphenylmethanamine

A small group of lipid-conjugated Smac mimetics was synthesized to probe the influence of the position of lipidation on overall anti-cancer activity. Specifically, new compounds were modified with lipid(s) in position 3 and C-terminus. Previously described position 2 lipidated analog M11 was also synthesized. The resulting mini library of Smacs lipidated in positions 2, 3 and C-terminus was screened extensively in vitro against a total number of 50 diverse cancer cell lines revealing that both the position of lipidation as well as the type of lipid, influence their anti-cancer activity and cancer type specificity. Moreover, when used in combination therapy with inhibitor of menin-MLL1 protein interactions, position 2 modified analog SM2 showed strong synergistic anti-cancer properties. The most promising lipid-conjugated analogs SM2 and SM6, showed favorable pharmacokinetics and in vivo activity while administered subcutaneously in the preclinical mouse model. Collectively, our findings suggest that lipid modification of Smacs may be a viable approach in the development of anti-cancer therapeutic leads.

Welcome to talk about 91-00-9, If you have any questions, you can contact Micewicz, ED; Nguyen, C; Micewicz, A; Waring, AJ; McBrid, WH; Ruchala, P or send Email.. Quality Control of Diphenylmethanamine

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Computed Properties of C13H13N. In 2019 EUR J ORG CHEM published article about ONE-POT SYNTHESIS; CATALYZED KNOEVENAGEL CONDENSATION; METAL-ORGANIC FRAMEWORK; FACILE SYNTHESIS; CHEMOSELECTIVE REDUCTION; GREEN PROCEDURE; IONIC LIQUID; EFFICIENT; NITRILES; HYDRATION in [Rupanawar, Bapurao D.; Suryavanshi, Gurunath] CSIR, Natl Chem Lab, Chem Engn & Proc Dev Div, Dr Homi Bhaba Rd, Pune 411008, Maharashtra, India; [Rupanawar, Bapurao D.; Suryavanshi, Gurunath] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, Uttar Pradesh, India; [Veetil, Sruthi M.] CSIR, Natl Chem Lab, Cent NMR Facil, Dr Homi Shaba Rd, Pune 411008, Maharashtra, India in 2019, Cited 74. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Hypervalent iodine-mediated oxidative olefination of amines with an active methylene compound provides a rapid gateway towards the formation of electrophilic alkenes under mild reaction conditions in good to excellent yields. This is an efficient protocol for the preparation of substituted electrophilic alkenes.

Welcome to talk about 91-00-9, If you have any questions, you can contact Rupanawar, BD; Veetil, SM; Suryavanshi, G or send Email.. Computed Properties of C13H13N

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

COA of Formula: C13H13N. Wang, L; Wang, XW; Hou, HB; Zhu, GQ; Han, ZY; Yang, WY; Chen, X; Wang, QG in [Wang, Liang; Wang, Xiaowu; Hou, Hongbin; Zhu, Guangqian; Han, Zhenyu; Yang, Weiying; Chen, Xiao; Wang, Qinggang] Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biobased Mat, Qingdao 266101, Peoples R China; [Zhu, Guangqian; Han, Zhenyu; Yang, Weiying] Univ Chinese Acad Sci, Ctr Mat Sci & Optoelect Engn, Beijing 100049, Peoples R China published An unsymmetrical binuclear iminopyridine-iron complex and its catalytic isoprene polymerization in 2020.0, Cited 51.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

A series of chloride-bridged unsymmetrical mixed Fe(ii)-HS/Fe(ii)-LS binuclear structures has been prepared and characterized. Upon activation with MAO, highly efficient catalytic polymerization of isoprene was achieved, delivering an ultra-high molecular weight (catalyst loading = 2.5 ppm,M-n= 1.8 x 10(6)g mol(-1),M-w/M-n= 1.4).

Welcome to talk about 91-00-9, If you have any questions, you can contact Wang, L; Wang, XW; Hou, HB; Zhu, GQ; Han, ZY; Yang, WY; Chen, X; Wang, QG or send Email.. COA of Formula: C13H13N

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Kita, Y; Kuwabara, M; Yamadera, S; Kamata, K; Hara, M in [Kita, Yusuke; Kuwabara, Midori; Yamadera, Satoshi; Kamata, Keigo; Hara, Michikazu] Tokyo Inst Technol, Lab Mat & Struct, Inst Innovat Res, Midori Ku, 4259 Nagatsuta Cho, Yokohama, Kanagawa 2268503, Japan; [Hara, Michikazu] Japan Sci & Technol Agcy JST, Adv Low Carbon Technol Res & Dev Program ALCA, 4-1-8 Honcho, Kawaguchi, Saitama 3320012, Japan published Effects of ruthenium hydride species on primary amine synthesis by direct amination of alcohols over a heterogeneous Ru catalyst in 2020.0, Cited 51.0. Name: Diphenylmethanamine. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Heterogeneously catalysed synthesis of primary amines by direct amination of alcohols with ammonia has long been an elusive goal. In contrast to reported Ru-based catalytic systems, we report that Ru-MgO/TiO(2)acts as an effective heterogeneous catalyst for the direct amination of a variety of alcohols to primary amines at low temperatures ofca.100 degrees C without the introduction of H(2)gas. The present system could be applied to a variety of alcohols and provides an efficient synthetic route for 2,5-bis(aminomethyl)furan (BAMF), an attention-getting biomonomer. The high catalytic performance can be rationalized by the reactivity tuning of Ru-H species using MgO. Spectroscopic measurements suggest that MgO enhances the reactivity of hydride species by electron donation from MgO to Ru.

Welcome to talk about 91-00-9, If you have any questions, you can contact Kita, Y; Kuwabara, M; Yamadera, S; Kamata, K; Hara, M or send Email.. Name: Diphenylmethanamine

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Deal;Structure-Activity Relationships of Benzamides and Isoindolines Designed as SARS-CoV Protease Inhibitors Effective against SARS-CoV-2 WOS:000577492100001 published article about CORONAVIRUS PAPAIN-LIKE; RESPIRATORY SYNDROME CORONAVIRUS; PNEUMONIA in [Welker, Armin; Sotriffer, Christoph] Justus Maximilians Univ Wurzburg, Inst Pharm & Food Chem, D-97074 Wurzburg, Germany; [Kersten, Christian; Zimmer, Collin; Mueller, Patrick; Zimmermann, Robert; Hammerschmidt, Stefan; Maus, Hannah; Schirmeister, Tanja] Johannes Gutenberg Univ Mainz, Inst Pharmaceut & Biomed Sci, Staudingerweg 5, D-55128 Mainz, Germany; [Mueller, Christin; Madhugiri, Ramakanth; Ziebuhr, John] Justus Liebig Univ Giessen, Inst Med Virol, Schubertstr 81, D-35392 Giessen, Germany in 2021.0, Cited 29.0. Computed Properties of C13H13N. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

Inhibition of coronavirus (CoV)-encoded papain-like cysteine proteases (PLpro) represents an attractive strategy to treat infections by these important human pathogens. Herein we report on structure-activity relationships (SAR) of the noncovalent active-site directed inhibitor (R)-5-amino-2-methyl-N-(1-(naphthalen-1-yl)ethyl) benzamide (2 b), which is known to bind into the S3 and S4 pockets of the SARS-CoV PLpro. Moreover, we report the discovery of isoindolines as a new class of potent PL(pro)inhibitors. The studies also provide a deeper understanding of the binding modes of this inhibitor class. Importantly, the inhibitors were also confirmed to inhibit SARS-CoV-2 replication in cell culture suggesting that, due to the high structural similarities of the target proteases, inhibitors identified against SARS-CoV PL(pro)are valuable starting points for the development of new pan-coronaviral inhibitors.

Computed Properties of C13H13N. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics