Tag: M.W=150-200

Nie, RF; Lai, RZ; Lv, SY; Xu, YY; Guo, L; Wang, QT; Wu, Y in [Wang, Qiantao; Wu, Yong] Sichuan Univ, Key Lab Drug Targeting & Drug Delivery Syst, Sichuan Engn Lab Plant Sourced Drug, Educ Minist,West China Sch Pharm, Chengdu 610041, Sichuan, Peoples R China; Sichuan Univ, Res Ctr Drug Ind Technol, Key Lab Drug Targeting & Drug Delivery Syst, Educ Minist,West China Sch Pharm, Chengdu 610041, Sichuan, Peoples R China published Water-mediated C-H activation of arenes with secure carbene precursors: the reaction and its application in 2019, Cited 50. Product Details of 91-00-9. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

A water-mediated C-H activation using sulfoxonium ylides is reported, providing a general, green and step-economic approach to construct a C-C bond and varieties of useful N-heterocycle scaffolds. Notably, the water-mediated activation, in contrast to that in organic solvents, shows great potential in pharmaceutical, biochemistry and chemical industries.

Product Details of 91-00-9. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Safety of Diphenylmethanamine. Recently I am researching about NUCLEOTIDE-BINDING-SITES; MULTIDRUG-RESISTANCE; AUTOMATED DOCKING; DRUG-RESISTANCE; FLEXIBLE LIGANDS; TRANSPORT; OPTIMIZATION; PURIFICATION; MTT; CHEMORESISTANCE, Saw an article supported by the National Institute of General Medical Sciences (NIH/NIGMS)United States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of General Medical Sciences (NIGMS) [R15 GM094771-02]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Wise, JG; Nanayakkara, AK; Aljowni, M; Chen, G; De Oliveira, MC; Ammerman, L; Olengue, K; Lippert, AR; Vogel, PD. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

Overexpression of ABC transporters like P-glycoprotein (P-gp) has been correlated with resistances in cancer chemotherapy. Intensive efforts to identify P-gp inhibitors for use in combination therapy have not led to clinically approved inhibitors to date. Here, we describe computational approaches combined with structure-based design to improve the characteristics of a P-gp inhibitor previously identified by us. This hit compound represents a novel class of P-gp inhibitors that specifically targets and inhibits P-gp ATP hydrolysis while not being transported by the pump. We describe here a new program for virtual chemical synthesis and computational assessment, ChemGen, to produce hit compound variants with improved binding characteristics. The chemical syntheses of several variants, efficacy in reversing multidrug resistance in cell culture, and biochemical assessment of the inhibition mechanism are described. The usefulness of the computational predictions of binding characteristics of the inhibitor variants is discussed and compared to more traditional structure-based approaches.

Welcome to talk about 91-00-9, If you have any questions, you can contact Wise, JG; Nanayakkara, AK; Aljowni, M; Chen, G; De Oliveira, MC; Ammerman, L; Olengue, K; Lippert, AR; Vogel, PD or send Email.. Safety of Diphenylmethanamine

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Metal-free Carbon Monoxide (CO) Capture and Utilization: Formylation of Amines published in 2019.0. COA of Formula: C13H13N, Reprint Addresses Jang, HY (corresponding author), Ajou Univ, Dept Energy Syst Res, Suwon 16499, South Korea.; Jung, J (corresponding author), Univ Ulsan, Dept Chem, Ulsan 44610, South Korea.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

The capture and utilization of CO by 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) were performed in the absence of transition-metal complexes. The reaction of TBD with CO afforded TBD-CO adducts, which were converted to formylated TBD (TBD-CHO). TBD-CO adducts may include an interaction of CO with positively charged species based on NMR and IR analysis. In the presence of amines, CO was transferred from TBD-CO to amines, producing formylated amines with good yields. The reaction mechanism involving TBD-CO adducts is presented based on theoretical calculations.

Welcome to talk about 91-00-9, If you have any questions, you can contact Noh, HW; An, Y; Lee, S; Jung, J; Son, SU; Jang, HY or send Email.. COA of Formula: C13H13N

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Category: amides-buliding-blocks. Hao, ZQ; Li, F; Gao, W in [Hao, Zhiqiang; Li, Feng; Gao, Wei] Jilin Univ, Coll Chem, Changchun 130012, Peoples R China; [Hao, Zhiqiang] Hebei Normal Univ, Coll Chem & Mat Sci, Hebei Key Lab Organ Funct Mol, Shijiazhuang 050024, Hebei, Peoples R China published o-Trityl phenoxy-imino vanadium (III) complexes: synthesis, characterization, and catalysis on ethylene (co)polymerization in 2020.0, Cited 56.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Several phenoxy-imine ligands bearing o-trityl group in phenoxy moiety RN=CHArOH (Ar = C6H2(CPh3)Bu-t, R = 2,6-Me2C6H3 (L1H); 2,6-(Pr2C6H3)-Pr-i (L2H); 3,5-(CF3)(2)C6H3 (L3H); 3,5-(OMe)(2)C6H3 (L4H); CHPh2 (L5H); CPh3 (L6H)) were synthesized and characterized by H-1 NMR and C-13 NMR spectroscopy. The vanadium complexes based on these ligands LVCl2(THF)(2) (1-6) were synthesized via conventional transmetalation reaction in moderate to high yields. Complexes 1-6 were fully characterized by FT-IR, elemental analyses and the molecular structures of 1, 2 center dot H2O, (2 center dot H2O)(2)(mu-Cl)(2), 4, and 5 were confirmed by X-ray crystallographic analysis in which the six-coordinated vanadium centers are in a typical octahedral geometry. Upon activation with Et2AlCl in toluene, complexes 1-6 showed high activities in ethylene polymerization affording polymers with moderate molecular weight (5.9-11.8 x 10(4) Da). Moreover, in hexane or CH2Cl2, 1-6/Et2AlCl exhibited enhanced activities. When activated with MAO or MMAO in toluene, these complexes showed relatively low activities but afforded polymers with ultra-high molecular weight (up to 3.30 x 10(6) Da). 1-6/Et2AlCl also showed high activities in ethylene/1-hexene copolymerization at room temperature giving moderate molecular-weight polymers (6.5-11.4 x 10(4) Da) with co-monomer incorporation being of 6.0 similar to 7.8%.

Category: amides-buliding-blocks. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Highly Active Chiral Dilithium(I) Binaphthyldisulfonate Catalysts for Enantio- and Chemoselective Strecker-Type Reactions published in 2019.0. HPLC of Formula: C13H13N, Reprint Addresses Ishihara, K (corresponding author), Nagoya Univ, Grad Sch Engn, Chikusa Ku, Furo Cho, Nagoya, Aichi 4648603, Japan.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

An enantioselective Strecker-type reaction of aldimines and ketimines was developed by using a chiral dilithium(I) binaphthyldisulfonate as a chiral acid-base cooperative catalyst. The present catalytic system features an extremely short reaction time (10 min to 4 h), unlike conventional catalytic systems. Along with the design of stronger chiral Li(I) Lewis acid catalysts, a highly reactive pentacoordinate silicate generated in situ could promote the reactions. In particular, instead of unstable N-Bn Strecker products, more stable N-CH2 (9-anthryl) and N-CH2 (1-naphthyl) Strecker products could be obtained in high yields with high enantioselectivities. By a switch of the present and previous catalyst systems, chemoselective cyanation to a ketoaldimine could be performed, respectively. Moreover, mechanistic investigations provided useful information regarding the active catalysts, catalytic cycles, and possible transition states.

HPLC of Formula: C13H13N. Welcome to talk about 91-00-9, If you have any questions, you can contact Hatano, M; Nishio, K; Mochizuki, T; Nishikawa, K; Ishihara, K or send Email.

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Scalable electrochemical oxidant-and metal-free dehydrogenative coupling of S-H/N-H published in 2019. Name: Diphenylmethanamine, Reprint Addresses Li, H; Yuan, BX (corresponding author), Zhengzhou Univ, Dept Chem & Mol Engn, Zhengzhou 450001, Henan, Peoples R China.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

A practical and scalable electrochemical oxidation of S-H and N-H was developed. This oxidant-and catalyst-free electrochemical process enables S-N bond formation with inexpensive nickel electrodes in an undivided cell. This procedure exhibits broad substrate scopes and good functional-group compatibility. A 50 g scale oxidative coupling augurs well for industrial applications.

Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.. Name: Diphenylmethanamine

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Pro-Phe Derivatives as Organocatalysts in Asymmetric Aldol Reaction WOS:000631153800009 published article about AQUEOUS-MEDIA; PROLINE; SOLVENT; DIPEPTIDES; CATALYSTS; ACETONE; WATER in [Karaoglu, Merve; Aydogan, Feray; Yolacan, Cigdem] Yildiz Tech Univ, Dept Chem, Davutpasa Campus, TR-34010 Istanbul, Turkey in 2021, Cited 53. Computed Properties of C13H13N. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

The aldol reaction which is the most important one among the C-C bond forming reactions, is widely used by synthetic organic chemists to obtain beta-hydroxycarbonyl compounds which are important starting components for biologically active compounds in optically pure form. In this research, five Pro-Phe derivatives were synthesized by simple amidation reactions and characterized by their spectral data. Their catalytic activities in asymmetric aldol reaction were investigated. The catalytic activity studies were performed with aliphatic ketones and various aromatic aldehydes. Especially, (S)methyl 3-mercapto-2-(S)-3-phenyl-2-((S)-pyrrolidine-2-carboxamido)propanamido)propanoate showed good catalytic activities in water at 0 degrees C in the presence of p-nitrobenzoic acid cocatalyst. The enantioselectivities were up to 90.4%, the diastereomeric ratios were up to 97/3 and yields were 99%. The results showed that these organocatalysts were promising organocatalysts for aldol reaction. Besides, this catalyst showed its best catalytic activities in water which is also an important contribution to green chemistry requirements.

Computed Properties of C13H13N. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Tertiary amine-directed and involved carbonylative cyclizations through Pd/Cu-cocatalyzed multiple C-X (X = H or N) bond cleavage WOS:000490984300010 published article about CATALYZED OXIDATIVE CARBONYLATION; DEALKYLATIVE CARBONYLATION; EFFICIENT SYNTHESIS; COUPLING REACTIONS; FUNCTIONALIZATION; PALLADIUM; ACTIVATION; ARYLATION; ACIDS; AMINOCARBONYLATION in [Mu, Qiu-Chao; Bai, Xing-Feng; Chen, Jing; Yang, Lei; Xia, Chun-Gu; Xu, Li-Wen] UCAS, LICP, SRI, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Gansu, Peoples R China; [Mu, Qiu-Chao; Nie, Yi-Xue; Bai, Xing-Feng; Yang, Lei; Xu, Zheng; Li, Li; Xu, Li-Wen] Hangzhou Normal Univ, Key Lab Organosilicon Mat Technol Zhejiang Prov, Key Lab Organosilicon Chem & Mat Technol, Minist Educ, Hangzhou 311121, Zhejiang, Peoples R China in 2019.0, Cited 97.0. Category: amides-buliding-blocks. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

A novel Pd/Cu-cocatalyzed carbonylative cyclization by C-H activation and N-dealkylative C-N bond activation has been developed for the chemoselective construction of synthetically useful heterocycles. The N,N-dimethylamine group on o-indolyl-N,N-dimethylarylamines was found to act as both the directing group and reactive component in this C-H carbonylative cyclization reaction. Furthermore, a unique C-H oxidation/carbonylative lactonization of diarylmethylamines is firstly demonstrated under modified reaction conditions, which could be easily applicable to the one-step synthesis of multi-substituted phthalides bearing an N,O-ketal skeleton that is difficult to access by previously reported methods. Mechanistic studies implicate that Pd/Cu-cocatalyzed C-H oxidation/carbonylative lactonization is a sequential reaction system via Cu-catalyzed C(sp(3))-H oxidation and Pd-catalyzed oxidative carbonylation of the C(sp(2))-H bond. It was found that trace amounts of water are essential to promote the Cu-catalyzed C(sp(3))-H oxidation of diarylmethylamine for the formation of the hydroxyl group, which could act as an in situ-formed directing group in the intramolecular carbonylative lactonization step.

Welcome to talk about 91-00-9, If you have any questions, you can contact Mu, QC; Nie, YX; Bai, XF; Chen, J; Yang, L; Xu, Z; Li, L; Xia, CG; Xu, LW or send Email.. Category: amides-buliding-blocks

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Authors Dan, DM; Chen, FB; Zhao, WS; Yu, H; Han, S; Wei, YG in ROYAL SOC CHEMISTRY published article about HOMOGENEOUS CATALYSIS; AEROBIC OXIDATION; CONVENIENT METHOD; FORMIC-ACID; HYDROGENATION; MILD; REAGENTS; OXYGEN; CO2 in [Dan, Demin; Yu, Han; Han, Sheng] Shanghai Inst Technol, Sch Chem & Environm Engn, Shanghai 201418, Peoples R China; [Chen, Fubo] Tongji Univ, Shanghai Peoples Hosp 10, Sch Med, Dept Stomatol, Shanghai 200072, Peoples R China; [Zhao, Whenshu] Shanghai Univ Tradit Chinese Med, Longhua Hosp, Shanghai 200000, Peoples R China; [Yu, Han; Wei, Yongge] Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Organ Optoelect & Mol Engn, Beijing 100081, Peoples R China; [Wei, Yongge] Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China in 2021.0, Cited 52.0. Computed Properties of C13H13N. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

A simple and efficient protocol for the formylation of amines with formic acid, catalyzed by a polyoxometalate-based chromium catalyst, is described. Notably, this method shows excellent activity and chemo-selectivity for the formylation of primary amines; diamines have also been successfully employed. Importantly, the chromium catalyst is potentially non-toxic, environmentally benign and safer than the widely used high valence chromium catalysts such as CrO3 and K2Cr2O7. The catalyst can be recycled several times with a negligible impact on activity. Finally, a plausible mechanism is provided based on the observation of intermediate and control experiments.

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Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Safety of Diphenylmethanamine. Tang, SY; Liu, Y; Li, LJ; Ren, XH; Li, J; Yang, GY; Li, H; Yuan, BX in [Tang, Shanyu; Li, Longjia; Ren, Xuanhe; Li, Jiao; Yang, Guanyu; Li, Heng; Yuan, Bingxin] Zhengzhou Univ, Dept Chem & Mol Engn, Zhengzhou 450001, Henan, Peoples R China; [Liu, Yan] Zhengzhou Univ, Sch Life Sci, Zhengzhou 450001, Henan, Peoples R China published Scalable electrochemical oxidant-and metal-free dehydrogenative coupling of S-H/N-H in 2019, Cited 44. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

A practical and scalable electrochemical oxidation of S-H and N-H was developed. This oxidant-and catalyst-free electrochemical process enables S-N bond formation with inexpensive nickel electrodes in an undivided cell. This procedure exhibits broad substrate scopes and good functional-group compatibility. A 50 g scale oxidative coupling augurs well for industrial applications.

Safety of Diphenylmethanamine. Welcome to talk about 91-00-9, If you have any questions, you can contact Tang, SY; Liu, Y; Li, LJ; Ren, XH; Li, J; Yang, GY; Li, H; Yuan, BX or send Email.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics