Tag: M.W=150-200

Recently I am researching about HOMOGENEOUS CATALYSIS; AEROBIC OXIDATION; CONVENIENT METHOD; FORMIC-ACID; HYDROGENATION; MILD; REAGENTS; OXYGEN; CO2, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21871183, 21631007, 21225103]; Doctoral Fund of Ministry of Education of ChinaMinistry of Education, China [20130002110042]; Tsinghua University Initiative Foundation Research Program [20131089204]; State Key Laboratory of Natural and Biomimetic Drugs [K20160202]; Shanghai Institute of Technology. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Dan, DM; Chen, FB; Zhao, WS; Yu, H; Han, S; Wei, YG. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine. COA of Formula: C13H13N

A simple and efficient protocol for the formylation of amines with formic acid, catalyzed by a polyoxometalate-based chromium catalyst, is described. Notably, this method shows excellent activity and chemo-selectivity for the formylation of primary amines; diamines have also been successfully employed. Importantly, the chromium catalyst is potentially non-toxic, environmentally benign and safer than the widely used high valence chromium catalysts such as CrO3 and K2Cr2O7. The catalyst can be recycled several times with a negligible impact on activity. Finally, a plausible mechanism is provided based on the observation of intermediate and control experiments.

Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.. COA of Formula: C13H13N

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Allylation and alkylation of oxindoleketimines via imine umpolung strategy published in 2021.0. Category: amides-buliding-blocks, Reprint Addresses Shen, MH; Xu, DF (corresponding author), Changzhou Univ, Sch Pharm, Jiangsu Key Lab Adv Catalyt Mat & Technol, Changzhou 213164, Jiangsu, Peoples R China.. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine

When treated with an alkoxide base like t-BuOK in aprotic solvent, N-diphenylmethyl imino oxindoles, made conveniently through condensation of corresponding isatins with N-diphenylmethyl amine, are deprotonated to form azaallyl anions. Allylation and alkylation of this type of intermediates proceed smoothly with diverse C-electrophiles. Acidic work up finishes 3-amino-3-allyl/alkyl oxindoles. The overall transformation equals to an umpolung process at the C3 of isatins. (c) 2021 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

Category: amides-buliding-blocks. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

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Amide – Wikipedia,
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An article Development and mechanistic investigation of the manganese(iii) salen-catalyzed dehydrogenation of alcohols WOS:000457342200020 published article about TRANSFER HYDROGENATION; SUBSTITUENT CONSTANTS; SUSTAINABLE SYNTHESIS; AMINES; LIGAND; KETONES; IRON; EPOXIDATION; ALKYLATION; EFFICIENT in [Samuelsen, SimoneV.; Santilli, Carola; Madsen, Robert] Tech Univ Denmark, Dept Chem, DK-2800 Lyngby, Denmark; [Ahlquist, Marten S. G.] KTH Royal Inst Technol, Dept Theoret Chem & Biol, Sch Engn Sci Chem Biotechnol & Hlth, S-10691 Stockholm, Sweden in 2019.0, Cited 64.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. Computed Properties of C13H13N

The first example of a manganese(III) catalyst for the acceptorless dehydrogenation of alcohols is presented. N,N’-Bis(salicylidene)-1,2-cyclohexanediaminomanganese(III) chloride (2) has been shown to catalyze the direct synthesis of imines from a variety of alcohols and amines with the liberation of hydrogen gas. The mechanism has been investigated experimentally with labelled substrates and theoretically with DFT calculations. The results indicate a metal-ligand bifunctional pathway in which both imine groups in the salen ligand are first reduced to form a manganese(III) amido complex as the catalytically active species. Dehydrogenation of the alcohol then takes place by a stepwise outer-sphere hydrogen transfer generating a manganese(III) salan hydride from which hydrogen gas is released.

Computed Properties of C13H13N. Welcome to talk about 91-00-9, If you have any questions, you can contact Samuelsen, S; Santilli, C; Ahlquist, MSG; Madsen, R or send Email.

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Amide – Wikipedia,
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SDS of cas: 91-00-9. Authors Karteek, SD; Reddy, AG; Tej, MB; Rao, MVB in MAIK NAUKA/INTERPERIODICA/SPRINGER published article about in [Karteek, S. Durga] Koneru Lakshmaiah Educ Fdn, Dept Chem, Vaddeswaram 522502, India; [Reddy, A. Gopi] SANA Coll Pharm, Dept Pharm, Kodad 508206, India; [Tej, M. Bhuvan] Sri Ramachandra Med Coll & Res Inst, Dept Pharm, Chennai 600116, Tamil Nadu, India; [Rao, M. V. Basaveswara] Krishna Univ, Dept Chem, Machilipatnam 521001, India in 2021.0, Cited 38.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

A new series of fused tricyclic coumarin derivatives were designed, synthesized by a simple and convenient method, starting from 4-hydroxycoumarin and virtually screened by molecular docking on the target protein 3FRZ (PDB ID: 3FRZ), a HCV RNA-dependent RNA polymerase, for potency against hepatitis C virus (HCV). Efficient binding to the target protein was found for most of the synthesized compounds.

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Kita, Y; Kuwabara, M; Yamadera, S; Kamata, K; Hara, M in [Kita, Yusuke; Kuwabara, Midori; Yamadera, Satoshi; Kamata, Keigo; Hara, Michikazu] Tokyo Inst Technol, Lab Mat & Struct, Inst Innovat Res, Midori Ku, 4259 Nagatsuta Cho, Yokohama, Kanagawa 2268503, Japan; [Hara, Michikazu] Japan Sci & Technol Agcy JST, Adv Low Carbon Technol Res & Dev Program ALCA, 4-1-8 Honcho, Kawaguchi, Saitama 3320012, Japan published Effects of ruthenium hydride species on primary amine synthesis by direct amination of alcohols over a heterogeneous Ru catalyst in 2020.0, Cited 51.0. COA of Formula: C13H13N. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Heterogeneously catalysed synthesis of primary amines by direct amination of alcohols with ammonia has long been an elusive goal. In contrast to reported Ru-based catalytic systems, we report that Ru-MgO/TiO(2)acts as an effective heterogeneous catalyst for the direct amination of a variety of alcohols to primary amines at low temperatures ofca.100 degrees C without the introduction of H(2)gas. The present system could be applied to a variety of alcohols and provides an efficient synthetic route for 2,5-bis(aminomethyl)furan (BAMF), an attention-getting biomonomer. The high catalytic performance can be rationalized by the reactivity tuning of Ru-H species using MgO. Spectroscopic measurements suggest that MgO enhances the reactivity of hydride species by electron donation from MgO to Ru.

COA of Formula: C13H13N. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Recently I am researching about STAPHYLOCOCCUS-AUREUS MRSA; POTENT TEIXOBACTIN ANALOGS; ANTIBACTERIAL ACTIVITY; IN-VITRO; ENDURACIDIDINE; SUBSTITUTION; RESIDUES; DESIGN, Saw an article supported by the SERB, New Delhi [EMR/2016/001045]; CSIR, New DelhiCouncil of Scientific & Industrial Research (CSIR) – India. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Gunjal, VB; Reddy, DS. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine. Application In Synthesis of Diphenylmethanamine

The total synthesis of cyclic depsipeptide Met(10)-teixobactin in solution-phase is described. Teixobactin is a structurally and mechanistically novel antimicrobial peptidic natural product with very impressive activities against Gram-positive pathogens. It happens to possess an L-allo-enduracididine (End) residue as part of macrocyclic ring which is not readily accessible. In this report, we have used serine ligation strategy as the key step to prepare an analogue of teixobactin where End being replaced with a readily available amino acid methionine. (C) 2019 Elsevier Ltd. All rights reserved.

Application In Synthesis of Diphenylmethanamine. Welcome to talk about 91-00-9, If you have any questions, you can contact Gunjal, VB; Reddy, DS or send Email.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Name: Diphenylmethanamine. In 2020.0 J MED CHEM published article about FATTY LIVER-DISEASE; DIET-INDUCED OBESITY; OXIDATIVE-PHOSPHORYLATION; METABOLIC-INHIBITORS; INSULIN-RESISTANCE; CANCER-CELLS; DINITROPHENOL; PROTON; MECHANISM; BIOENERGETICS in [Hargett, Stefan R.; Hoehn, Kyle L.] Univ Virginia, Dept Pharmacol, Charlottesville, VA 22908 USA; [Hargett, Stefan R.; Hoehn, Kyle L.] Univ Virginia, Dept Med, Charlottesville, VA 22908 USA; [Chen, Sing-Young; Beretta, Martina; Alexopoulos, Stephanie J.; Shah, Divya P.; Olzomer, Ellen M.; Hoehn, Kyle L.] Univ New South Wales, Sch Biotechnol & Biomol Sci, Kensington, NSW 2033, Australia; [Salamoun, Joseph M.; Garcia, Christopher J.; Murray, Jacob H.; Santos, Webster L.] Virginia Tech, Dept Chem, Blacksburg, VA 24061 USA; [Salamoun, Joseph M.; Garcia, Christopher J.; Murray, Jacob H.; Santos, Webster L.] Virginia Tech, Virginia Tech Ctr Drug Discovery, Blacksburg, VA 24061 USA; [Tucker, Simon P.] Continuum Biosci Pty Ltd, Sydney, NSW 2035, Australia; [Tucker, Simon P.] Continuum Biosci Inc, Boston, MA 02116 USA in 2020.0, Cited 93.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Small molecule mitochondrial uncouplers have recently garnered great interest for their potential in treating nonalcoholic steatohepatitis (NASH). In this study, we report the structure-activity relationship profiling of a 6-amino[1,2,5]oxadiazolo[3,4-b]pyrazin-5-ol core, which utilizes the hydroxy moiety as the proton transporter across the mitochondrial inner membrane. We demonstrate that a wide array of substituents is tolerated with this novel scaffold that increased cellular metabolic rates in vitro using changes in oxygen consumption rate as a readout. In particular, compound SHS4121705 (12i) displayed an EC50 of 4.3 mu M in L6 myoblast cells and excellent oral bioavailability and liver exposure in mice. In the STAM mouse model of NASH, administration of 12i at 25 mg kg(-1) day(-1) lowered liver triglyceride levels and improved liver markers such as alanine aminotransferase, NAFLD activity score, and fibrosis. Importantly, no changes in body temperature or food intake were observed. As potential treatment of NASH, mitochondrial uncouplers show promise for future development.

Name: Diphenylmethanamine. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

Recently I am researching about EFFICIENT SYNTHESIS; 2,3-DIHYDROQUINAZOLIN-4(1H)-ONES; INHIBITORS; CHEMISTRY; SYNTHASE, Saw an article supported by the CHRIST [MRPDSC-1723]. Published in TAYLOR & FRANCIS INC in PHILADELPHIA ,Authors: Jaganmohan, C; Kumar, KPV; Venkateshwarlu, R; Mohanty, S; Kumar, J; Rao, BV; Raghunadh, A; Tadiparthi, K. The CAS is 91-00-9. Through research, I have a further understanding and discovery of Diphenylmethanamine. Product Details of 91-00-9

A new metal-free and modular approach for the synthesis of various functionalized dihydroquinazolinones has been developed from isatoic anhydride, amines, 4-chloro-N-hydroxybenzimidoylchloride to yield up to 71%. The reaction has been screened in various bases, solvents at different temperatures. The substrate scope of the reaction has been studied with various amines and the possible reaction mechanism for this reaction has also been proposed.

Product Details of 91-00-9. Welcome to talk about 91-00-9, If you have any questions, you can contact Jaganmohan, C; Kumar, KPV; Venkateshwarlu, R; Mohanty, S; Kumar, J; Rao, BV; Raghunadh, A; Tadiparthi, K or send Email.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Mild Iridium-Catalysed Isomerization of Epoxides. Computational Insights and Application to the Synthesis of beta-Alkyl Amines WOS:000474106100001 published article about MEINWALD REARRANGEMENT REACTIONS; PROMOTED REARRANGEMENT; SELECTIVE SYNTHESIS; CONVERSION; CYCLOPROPANES; CARBONYLATION; COMPLEXES; OXIDATION; ALDEHYDES in [Cabre, Albert; Cabezas-Gimenez, Juanjo; Verdaguer, Xavier; Riera, Antoni] Inst Res Biomed IRB Barcelona, Baldiri Reixac 10, Barcelona 08028, Spain; [Cabre, Albert; Cabezas-Gimenez, Juanjo; Verdaguer, Xavier; Riera, Antoni] Univ Barcelona, Dept Quim Inorgan & Organ, Seccio Organ, Marti i Franques 1, E-08028 Barcelona, Spain; [Sciortino, Giuseppe; Ujaque, Gregori; Lledos, Agusti] Univ Autonoma Barcelona, Dept Quim, Edifici Cn, Cerdanyola Del Valles 08193, Spain; [Sciortino, Giuseppe] Univ Sassari, Dipt Chim & Farm, Via Vienna 2, I-07017 Sassari, Italy in 2019.0, Cited 58.0. HPLC of Formula: C13H13N. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

The isomerization of epoxides to aldehydes using the readily available Crabtree’s reagent is described. The aldehydes were transformed into synthetically useful amines by a one-pot reductive amination using pyrrolidine as imine-formation catalyst. The reactions worked with low catalyst loadings in very mild conditions. The procedure is operationally simple and tolerates a wide range of functional groups. A DFT study of its mechanism is presented showing that the isomerization takes place via an iridium hydride mechanism with a low energy barrier, in agreement with the mild reaction conditions.

Welcome to talk about 91-00-9, If you have any questions, you can contact Cabre, A; Cabezas-Gimenez, J; Sciortino, G; Ujaque, G; Verdaguer, X; Lledos, A; Riera, A or send Email.. HPLC of Formula: C13H13N

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Ambient Reductive Amination of Levulinic Acid to Pyrrolidones over Pt Nanocatalysts on Porous TiO2 Nanosheets WOS:000460996500037 published article about HIGHLY EFFICIENT CATALYST; NITROGEN-COMPOUNDS; PRECIOUS-METAL; PRIMARY AMINES; KETO ACIDS; BIOMASS; HYDROGENATION; AMINATION/CYCLIZATION; HYDRODEOXYGENATION; TRANSFORMATION in [Xie, Chao; Song, Jinliang; Wu, Haoran; Hu, Yue; Liu, Huizhen; Zhang, Zhanrong; Zhang, Pei; Chen, Bingfeng; Han, Buxing] Chinese Acad Sci, Inst Chem, CAS Res Educ Ctr Excellence Mol Sci, Beijing Natl Lab Mol Sci,CAS Key Lab Colloid & In, Beijing 100190, Peoples R China; [Xie, Chao; Wu, Haoran; Hu, Yue; Liu, Huizhen; Han, Buxing] Univ Chinese Acad Sci, Sch Chem & Chem Engn, Beijing 100049, Peoples R China in 2019.0, Cited 50.0. Product Details of 91-00-9. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

Construction of N-substituted pyrrolidones from biomass-derived levulinic acid (LA) via reductive amination is a highly attractive route for biomass valorization. However, realizing this transformation using H-2 as the hydrogen source under mild conditions is still very challenging. Herein, we designed porous TiO2 nanosheets-supported Pt nanoparticles (Pt/P-TiO2) as the heterogeneous catalyst. The prepared Pt/P-TiO2 was highly efficient for reductive amination of LA to produce various N-substituted pyrrolidones (34 examples) at ambient temperature and H-2 pressure. Meanwhile, Pt/P-TiO2 showed good applicability for reductive amination of levulinic esters, 4-acetylbutyric acid, 2-acetylbenzoic acid, and 2-carboxybenzaldehyde. Systematic studies indicated that the strong acidity of P-TiO2 and the lower electron density of the Pt sites as well as the porous structure resulted in the excellent activity of Pt/P-TiO2.

Product Details of 91-00-9. Welcome to talk about 91-00-9, If you have any questions, you can contact Xie, C; Song, JL; Wu, HR; Hu, Y; Liu, HZ; Zhang, ZR; Zhang, P; Chen, BF; Han, BX or send Email.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics