Tag: M.W=150-200

COA of Formula: C13H13N. Authors Liang, XY; Yu, P; Fu, C; Shen, YC in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Liang, Xiayu; Yu, Peng; Fu, Chen; Shen, Yongcun] Wuhan Univ Technol, Sch Chem Chem Engn & Life Sci, 122 Luoshi Rd, Wuhan 430070, Peoples R China in 2021, Cited 31. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9

A new strategy for the facile synthesis of hydroxyalkylamides through the ring-opening reaction of lactone with amine promoted by dibutyltin acetate was developed. A series of hydroxyalkylamide compounds were obtained and the method was successfully applied to the synthesis of pharmaceutically active molecules tyrosinase inhibitor V and HDAC inhibitor VI via a three-step synthetic pathway. The broad substrate scope, mild reaction conditions and practical application proved the effectiveness, compatibility and practicality of this method. (C) 2021 Elsevier Ltd. All rights reserved.

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Amide – Wikipedia,
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HPLC of Formula: C13H13N. In 2019 SCIENCE published article about THERMOCHEMICAL KINETICS; EQUILIBRIUM ACIDITIES; DENSITY FUNCTIONALS; CONJUGATE ADDITION; MICHAEL ADDITION; DIAZO-COMPOUNDS; BASIS-SETS; CATALYSIS; CARBON; ORGANOCATALYSTS in [Zhu, Shou-Fei; Zhou, Qi-Lin] Nankai Univ, Coll Chem, State Key Lab, Tianjin 300071, Peoples R China; Nankai Univ, Coll Chem, Inst Elementoorgan Chem, Tianjin 300071, Peoples R China in 2019, Cited 67. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Aliphatic amines strongly coordinate, and therefore easily inhibit, the activity of transition-metal catalysts, posing a marked challenge to nitrogen-hydrogen (N-H) insertion reactions. Here, we report highly enantioselective carbene insertion into N-H bonds of aliphatic amines using two catalysts in tandem: an achiral copper complex and chiral amino-thiourea. Coordination by a homoscorpionate ligand protects the copper center that activates the carbene precursor. The chiral amino-thiourea catalyst then promotes enantioselective proton transfer to generate the stereocenter of the insertion product. This reaction couples a wide variety of diazo esters and amines to produce chiral alpha-alkyl alpha-amino acid derivatives.

Welcome to talk about 91-00-9, If you have any questions, you can contact Li, ML; Yu, JH; Li, YH; Zhu, SF; Zhou, QL or send Email.. HPLC of Formula: C13H13N

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Formula: C13H13N. Dodo, K; Kuboki, E; Shimizu, T; Imamura, R; Magarisawa, M; Takahashi, M; Tokuhiro, T; Yotsumoto, S; Asano, K; Nakao, S; Terayama, N; Suda, T; Tanaka, M; Sodeoka, M in [Dodo, Kosuke; Shimizu, Tadashi; Nakao, Shuhei; Terayama, Naoki; Sodeoka, Mikiko] RIKEN Cluster Pioneering Res, Synthet Organ Chem Lab, 2-1 Hirosawa, Wako, Saitama 3510198, Japan; [Dodo, Kosuke; Sodeoka, Mikiko] JST, ERATO, Sodeoka Live Cell Chem Project, 2-1 Hirosawa, Wako, Saitama 3510198, Japan; [Dodo, Kosuke; Shimizu, Tadashi; Takahashi, Masahiro; Sodeoka, Mikiko] Tohoku Univ, IMRAM, Aoba Ku, 2-1-1 Katahira, Sendai, Miyagi 9808577, Japan; [Kuboki, Erika; Magarisawa, Megumi; Tokuhiro, Takuto; Yotsumoto, Satoshi; Asano, Kenichi; Tanaka, Masato] Tokyo Univ Pharm & Life Sci, Sch Life Sci, Lab Immune Regulat, HAC, 1432-1 Horinouchi, Tokyo 1920392, Japan; [Imamura, Ryu; Suda, Takashi] Kanazawa Univ, Canc Res Inst, Div Immunol & Mol Biol, Kakuma Machi, Kanazawa, Ishikawa 9201192, Japan; [Shimizu, Tadashi] Hyogo Univ Hlth Sci, Adv Med Res Ctr, 1-3-6 Minatojima, Kobe, Hyogo 6508530, Japan published Development of a Water-Soluble Indolylmaleimide Derivative IM-93 Showing Dual Inhibition of Ferroptosis and NETosis in 2019.0, Cited 31.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

The indolylmaleimide (IM) derivative IM-17 shows inhibitory activity against oxidative-stress-induced necrotic cell death and cardioprotective activity in rat ischemia-reperfusion injury models. In order to develop a more potent derivative, we conducted a detailed structure-activity relationship study of IM derivatives and identified IM 93 as the most potent derivative with good water solubility. IM-93 inhibited ferroptosis and NETosis, but not necroptosis or pyroptosis. In contrast, ferrostatin-1 (Fer-1), a ferroptosis inhibitor, did not inhibit NETosis, although the accompanying lipid peroxidation was partially inhibited by Fer-1, as well as by IM-93. Thus, IM derivatives have a unique activity profile and appear to be promising candidates for in vivo application.

Formula: C13H13N. Welcome to talk about 91-00-9, If you have any questions, you can contact Dodo, K; Kuboki, E; Shimizu, T; Imamura, R; Magarisawa, M; Takahashi, M; Tokuhiro, T; Yotsumoto, S; Asano, K; Nakao, S; Terayama, N; Suda, T; Tanaka, M; Sodeoka, M or send Email.

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Micewicz, ED; Nguyen, C; Micewicz, A; Waring, AJ; McBrid, WH; Ruchala, P in [Micewicz, Ewa D.; Nguyen, Christine; McBrid, William H.] Univ Calif Los Angeles, Dept Radiat Oncol, 10833 Le Conte Ave, Los Angeles, CA 90095 USA; [Micewicz, Alina] Univ Calif Los Angeles, David Geffen Sch Med, Volunteering Program, 10833 Le Conte Ave, Los Angeles, CA 90095 USA; [Waring, Alan J.] Harbor UCLA Med Ctr, Dept Med, Los Angeles Biomed Res Inst, 1000 West Carson St, Torrance, CA 90502 USA; [Ruchala, Piotr] Univ Calif Los Angeles, Dept Psychiat & Biobehav Sci, 760 Westwood Plaza, Los Angeles, CA 90024 USA; [Ruchala, Piotr] Jane & Terry Semel Inst Neurosci & Human Behav, Pasarow Mass Spectrometry Lab, 760 Westwood Plaza, Los Angeles, CA 90024 USA published Position of lipidation influences anticancer activity of Smac analogs in 2019.0, Cited 79.0. Category: amides-buliding-blocks. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

A small group of lipid-conjugated Smac mimetics was synthesized to probe the influence of the position of lipidation on overall anti-cancer activity. Specifically, new compounds were modified with lipid(s) in position 3 and C-terminus. Previously described position 2 lipidated analog M11 was also synthesized. The resulting mini library of Smacs lipidated in positions 2, 3 and C-terminus was screened extensively in vitro against a total number of 50 diverse cancer cell lines revealing that both the position of lipidation as well as the type of lipid, influence their anti-cancer activity and cancer type specificity. Moreover, when used in combination therapy with inhibitor of menin-MLL1 protein interactions, position 2 modified analog SM2 showed strong synergistic anti-cancer properties. The most promising lipid-conjugated analogs SM2 and SM6, showed favorable pharmacokinetics and in vivo activity while administered subcutaneously in the preclinical mouse model. Collectively, our findings suggest that lipid modification of Smacs may be a viable approach in the development of anti-cancer therapeutic leads.

Category: amides-buliding-blocks. Welcome to talk about 91-00-9, If you have any questions, you can contact Micewicz, ED; Nguyen, C; Micewicz, A; Waring, AJ; McBrid, WH; Ruchala, P or send Email.

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Formula: C13H13N. In 2021.0 RUSS J ORG CHEM+ published article about PHOTOCHEMISTRY; COMPLEXES in [Li, J.; Xing, J. D.; Shi, Y. B.] Taiyuan Univ Technol, Sch Biomed Engn, Taiyuan 030000, Peoples R China in 2021.0, Cited 25.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Proton transfer processes mediate many organic reactions. How to realize stereochemical control of this process has always been a challenging topic in the field of asymmetric catalysis. In this study, N-(diphenylmethyl)-1-phenylethan-1-imine (Schiff base derived from 2,2-diphenylethan-1-amine and acetophenone) was used as substrate, and different near neutral solvents and various chiral metal complex catalysts were used to carry out photoinduced C=N double bond transfer in the substrate under irradiation with a mercury ultraviolet lamp. The double bond transfer in the substrate molecule was highly selective. Solvents containing strong electronegative atoms like oxygen and chlorine, such as alcohols, aldehydes, and carbon tetrachloride, were more effective than other solvents under high light intensity. The 1,3-proton transfer process involves photoexcitation of the Schiff base and coordination of the latter to the central metal atom of the chiral catalyst, so that the substrate molecule is placed in a stable chiral environment to form a transition state. The strongly electronegative atom of the near-neutral solvent attracts the active a-hydrogen from the excited Schiff base molecule to form a negatively charged delocalized p-bond structure. The subsequent proton addition yields more stable molecular structure to complete the selective proton transfer process. Among the examined chiral catalysts, divalent tin porphyrin was the most effective, and the product yield and enantiomeric excess were 98% and 91.49%, respectively. The described photoinduced C=N double bond transfer in N-(diphenylmethyl)-1-phenylethan-1-imine is characterized by mild conditions (room temperature), high stereoselectivity, and simple operation.

Formula: C13H13N. Welcome to talk about 91-00-9, If you have any questions, you can contact Li, J; Xing, JD; Shi, YB or send Email.

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Amide – Wikipedia,
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An article Highly Active Chiral Dilithium(I) Binaphthyldisulfonate Catalysts for Enantio- and Chemoselective Strecker-Type Reactions WOS:000485090400053 published article about TRIMETHYLSILYL CYANIDE; ENANTIOSELECTIVE CYANOSILYLATION; PRACTICAL SYNTHESIS; AMINO-ACIDS; CYANATION; IMINES; PENTACOORDINATE; HYDROCYANATION; REACTIVITY; ALDIMINES in [Hatano, Manabu; Nishio, Kosuke; Mochizuki, Takuya; Nishikawa, Keisuke; Ishihara, Kazuaki] Nagoya Univ, Grad Sch Engn, Chikusa Ku, Furo Cho, Nagoya, Aichi 4648603, Japan in 2019.0, Cited 84.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. COA of Formula: C13H13N

An enantioselective Strecker-type reaction of aldimines and ketimines was developed by using a chiral dilithium(I) binaphthyldisulfonate as a chiral acid-base cooperative catalyst. The present catalytic system features an extremely short reaction time (10 min to 4 h), unlike conventional catalytic systems. Along with the design of stronger chiral Li(I) Lewis acid catalysts, a highly reactive pentacoordinate silicate generated in situ could promote the reactions. In particular, instead of unstable N-Bn Strecker products, more stable N-CH2 (9-anthryl) and N-CH2 (1-naphthyl) Strecker products could be obtained in high yields with high enantioselectivities. By a switch of the present and previous catalyst systems, chemoselective cyanation to a ketoaldimine could be performed, respectively. Moreover, mechanistic investigations provided useful information regarding the active catalysts, catalytic cycles, and possible transition states.

COA of Formula: C13H13N. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

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Amide – Wikipedia,
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Quality Control of Diphenylmethanamine. Naqvi, S; Kumar, M; Kumar, R in [Naqvi, Samya; Kumar, Rachana] CSIR Natl Phys Lab, Adv Mat & Devices Metrol Div, Photovolta Metrol Grp, Dr KS Krishnan Marg, New Delhi 110012, India; [Kumar, Mahesh] CSIR Natl Phys Lab, Adv Mat & Devices Metrol Div, Photon Mat Metrol Grp, Dr KS Krishnan Marg, New Delhi 110012, India published Facile Synthesis and Evaluation of Electron Transport and Photophysical Properties of Photoluminescent PDI Derivatives in 2019.0, Cited 83.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9.

Perylenediimides (PDIs) have emerged as potential materials for optoelectronic applications. In the current work, four PDI derivatives, substituted at imide nitrogen with 2,6-diisopropyl phenyl, 2-nitrophenyl, diphenylmethylene, and pentafluorophenyl groups, have been synthesized from perylene 3,4,9,10-tetracarboxylic dianhydride using a facile imidization synthesis process. PDI derivatives have been spectroscopically characterized for their structure and optical properties. Temperature-variable absorption and emission spectroscopy study confirmed the H-aggregation property. H-aggregation along with strong emission suggests the slipped pi-pi stacking of PDI molecules. Electrochemical analysis was performed for their redox behavior and calculation of lowest unoccupied molecular orbital and highest occupied molecular orbital energy levels. Scanning electron microscopy showed the formation of ordered structures. The PDI derivatives showed excellent electron conductivity without doping and 5-10x higher electron mobility than that of state-of-the-art fullerene acceptor phenyl-C-61 -butyric acid methyl ester (PC61BM). Finally, the charge generation and charge transfer phenomenon was studied by transient absorption spectroscopy (TAS). TAS showed ultrafast charge transfer from the poly(3-hexyl)thiophene (P3HT) donor polymer to PDI and formation of long-lived charge-separated states similar to fullerene derivative PC61 BM/P3HT blends. Such PDI derivatives with excellent solubility and photophysical and electronic properties are potential n-type materials to be used in organic electronic devices.

Quality Control of Diphenylmethanamine. Welcome to talk about 91-00-9, If you have any questions, you can contact Naqvi, S; Kumar, M; Kumar, R or send Email.

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Iron-Catalyzed Direct Transformation of Benzylic Amines into Carbonyl Compounds in Water WOS:000482516100016 published article about DIRECT N-ALKYLATION; OXIDATIVE DEAMINATION; BOND-CLEAVAGE; METAL-FREE; MECHANISM; QUINAZOLINONES; HYDROGENATION; ALCOHOLS; ACIDS; SCOPE in [Minakawa, Maki; Sasaki, Takashi] Yamagata Univ, Dept Appl Chem Chem Engn & Biochem Engn, 4-3-16 Jonan, Yonezawa, Yamagata 9928510, Japan in 2019, Cited 32. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. Recommanded Product: 91-00-9

Fe-catalyzed direct transformation of benzylic amines into carbonyl compounds was performed in H2O. The reaction of benzylic amines with formaldehyde in the presence of FeCl3 center dot 6H(2)O in H2O afforded the corresponding carbonyl compounds (80 degrees C to reflux conditions; 14 examples, up to 94% yield). O-18-labeling experiments indicated that the O atom in the generated carbonyl is derived from H2O.

Recommanded Product: 91-00-9. Welcome to talk about 91-00-9, If you have any questions, you can contact Minakawa, M; Sasaki, T or send Email.

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Amide – Wikipedia,
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An article Synthesis of New 1,3,5-Azadiphosphorinanes Based on Aliphatic Amines WOS:000522647800009 published article about CYCLIC AMINOMETHYLPHOSPHINES; COMPLEXES in [Musina, E. I.; Musin, L. I.; Litvinov, I. A.; Karasik, A. A.] Russian Acad Sci, Kazan Sci Ctr, Fed Res Ctr, AE Arbuzov Inst Organ & Phys Chem, Kazan 420088, Russia in 2020.0, Cited 25.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. Safety of Diphenylmethanamine

New 1-aza-3,5-diphosphorinanes have been synthesized as a mixture of RR/SS- and RS-isomers via the reaction of bis(phenylphosphanyl)methane, paraformaldehyde, isopropylamine, of benzhydrylamine.

Safety of Diphenylmethanamine. About Diphenylmethanamine, If you have any questions, you can contact Musina, EI; Musin, LI; Litvinov, IA; Karasik, AA or concate me.

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Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics

An article Catalytic Enantioselective Synthesis of 4-Amino-1,2,3,4-tetrahydropyridine Derivatives from Intramolecular Nucleophilic Addition Reaction of Tertiary Enamides WOS:000459590400024 published article about FORMYLMETHYL-SUBSTITUTED ENAMIDES; HIGHLY EFFICIENT; BRONSTED ACID; DIASTEREOSELECTIVE SYNTHESIS; BETA-HYDROXY; CYCLOADDITION; BIOTRANSFORMATIONS; PIPERIDINES; CYCLIZATION; PYRIDINES in [Tong, Shuo; Wang, Mei-Xiang] Tsinghua Univ, Dept Chem, MOE Key Lab Bioorgan Phosphorous Chem & Chem Biol, Beijing 100084, Peoples R China in 2019.0, Cited 54.0. The Name is Diphenylmethanamine. Through research, I have a further understanding and discovery of 91-00-9. Application In Synthesis of Diphenylmethanamine

A general and efficient method for the synthesis of highly enantiopure 4-amino-1,2,3,4-tetradydropyridine derivatives based on chiral phosphoric acid catalyzed intramolecular nucleophilic addition of tertiary enamides to imines has been developed. We have also demonstrated a substrate engineering strategy to significantly improve the enantioselectivity of asymmetric catalysis

Application In Synthesis of Diphenylmethanamine. Bye, fridends, I hope you can learn more about C13H13N, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics