Chemistry is an experimental science, Application In Synthesis of Benzenesulfonamide, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 98-10-2, Name is Benzenesulfonamide, molecular formula is C6H7NO2S, belongs to amides-buliding-blocks compound. In a document, author is Li, Yiming.
The recombinant polyhistidine-tagged hemoglobin I ((His)(6)-rHbI) from the bivalve Lucina pectinata is an ideal biocomponent for a hydrogen sulfide (H2S) biosensor due to its high affinity for H2S. In this work, we immobilized (His)(6)-rHbI over a surface modified with gold nanoparticles functionalized with 3-mercaptopropionic acid complexed with nickel ion. The attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) analysis of the modified-gold electrode displays amide I and amide II bands characteristic of a primarily alpha-helix structure verifying the presence of (His)(6)-rHbI on the electrode surface. Also, X-ray photoelectron spectroscopy (XPS) results show a new peak after protein interaction corresponding to nitrogen and a calculated overlayer thickness of 5.3 nm. The functionality of the immobilized hemoprotein was established by direct current potential amperometry, using H2S as the analyte, validating its activity after immobilization. The current response to H2S concentrations was monitored over time giving a linear relationship from 30 to 700 nM with a corresponding sensitivity of 3.22 x 10(-3) nA/nM. These results confirm that the analyzed gold nanostructured platform provides an efficient and strong link for polyhistidine-tag protein immobilization over gold and glassy carbon surfaces for a future biosensors development.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 98-10-2. Application In Synthesis of Benzenesulfonamide.
Reference:
Amide – Wikipedia,
,Amide – an overview | ScienceDirect Topics